Results 121 to 130 of about 120,121 (346)
Expression of Cd34 and Myf5 Defines the Majority of Quiescent Adult Skeletal Muscle Satellite Cells
Journal of Cell Biology, 2000 Skeletal muscle is one of a several adult post-mitotic tissues that retain the capacity to regenerate. This relies on a population of quiescent precursors, termed satellite cells.
J. Beauchamp +8 more
semanticscholar +1 more source
Satellite Cell Proliferative Compartments in Growing Skeletal Muscles
Developmental Biology, 1996 The cell cycle time of satellite cells in growing rats was determined to be approximately 32 hr, with an S-phase of 14 hr. The estimated cycle time was the same for satellite cells in both oxidative soleus and glycolytic EDL muscles and is consistent with the rate at which myonuclei are produced during growth.
openaire +2 more sources
The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity
AGING MEDICINE, EarlyView.Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley +1 more source
Isolation of Myogenic Nuclei from Whole Muscle Tissue [PDF]
, 2015 Isolation of myogenic cell populations from whole skeletal muscle is necessary to elucidate the molecular repair mechanisms involved in skeletal muscle maintenance and regeneration that can be damaged when affected by diseases or aging, often severely ...
Brewer, Owen
core +2 more sources
Towards Advanced Intelligent and Perceptive Soft Grippers
Advanced Intelligent Systems, EarlyView.Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim +4 more
wiley +1 more source
Nature Communications, 2018 “Satellite cells are crucial for skeletal muscle regeneration. Here the authors show that immunoglobulin superfamily containing leucine-rich repeat (Islr) promotes skeletal muscle regeneration via a mechanism involving Dishevelled-2 stabilization in ...
Kuo Zhang +17 more
doaj +1 more source
Peripheral endocannabinoids regulate skeletal muscle development and maintenance
European Journal of Translational Myology, 2010 As a principal tissue responsible for insulin-mediated glucose uptake, skeletal muscle is important for whole-body health. The role of peripheral endocannabinoids as regulators of skeletal muscle metabolism has recently gained a lot of interest, as ...
Dongjiao Zhao +6 more
doaj +1 more source
Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]
, 2019 Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John +2 more
core +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells
Stem Cell Reports, 2018 Summary: Adult muscle stem cells (satellite cells) are required for adult skeletal muscle regeneration. A proper balance between quiescence, proliferation, and differentiation is essential for the maintenance of the satellite cell pool and their ...
Yasuo Kitajima +9 more
doaj +1 more source