Results 271 to 280 of about 120,121 (346)

Global MyoG research 2004-2024: a bibliometric analysis of trends and translational implications. [PDF]

Exp Biol Med (Maywood)
Hu L, Zhuang W, Chen W, Yang S, Chen S, Wang X, Gao Q, Chen J.   +7 more
europepmc   +1 more source

Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology‐Specific End‐Stage Liver Disease

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic ...
Thomas Nicholson, Sophie L. Allen, Jonathan I. Quinlan, Amritpal Dhaliwal, Michael Macleod, Joshua Price, Jon Hazeldine, Michael S. Sagmeister, Caitlin Ditchfield, Kirsty C. McGee, Felicity R. Williams, Ahmed M. Elsharkawy, Matthew J. Armstrong, Carolyn A. Greig, Janet M. Lord, Leigh Breen, Simon W. Jones   +16 more
wiley   +1 more source

Pharmacological Inhibition of N-terminal methyltransferase 1 promotes myogenic differentiation and muscle regeneration in a mouse model of Duchenne muscular dystrophy. [PDF]

Stem Cell Res Ther
Zhang H, He M, Asif M, Deng Y, Huang R, Kuang S.   +5 more
europepmc   +1 more source

Deubiquitinase YOD1 Inhibition Suppresses DEX‐ and Denervation‐Induced Muscle Atrophy Through MAFbx Destabilization

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Backgrounds Muscle atrophy, characterized by progressive loss of muscle mass and function, is driven by muscle‐specific E3 ligases MAFbx and MuRF1. While transcriptional regulation of E3 ligases is documented, the mechanism of their regulation by the ubiquitin–proteasome system remains unclear. This study aims to identify a deubiquitinase (DUB)
Jongbeom Chae, Seon Min Woo, Seung Un Seo, Simmyung Yook, Hyo Je Cho, Jung Yeol Lee, Kyoung jin Min, Junhyeon Park, Dongryeol Ryu, Taeg Kyu Kwon   +9 more
wiley   +1 more source

The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva. [PDF]

Bone
Hanson LR, Scalise KL, Esch RM, Nevo L, Goldhamer DJ.   +4 more
europepmc   +1 more source

Ageing‐Associated Dysregulation of Myogenic Differentiation in Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Skeletal muscle is a postmitotic tissue dependent on a complex and tightly regulated regeneration process involving numerous intracellular and extracellular factors, including myogenic regulatory factors (MRFs), cytokines and myokines. Quiescent satellite cells are activated by physiological stimuli, injury or other traumatic insults for the ...
Geert M. de Vries, Willem De Ridder, Jonathan Baets   +2 more
wiley   +1 more source

Mustn1 ablation in male mice results in fiber type and gene expression alterations during skeletal muscle regeneration. [PDF]

Physiol Rep
Tagliaferri K, Thomas N, Atallah M, Triantafillou S, Hadjiargyrou M.   +4 more
europepmc   +1 more source

Elevated Circulating Ceramides 18:0 and 24:1 as a Risk Factor for Sarcopenia: In Vitro, Animal, and Clinical Evidence

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline. Among these, C18:0 and C24:1 ceramides may play a role in the pathophysiology of sarcopenia, a key manifestation of age‐related deterioration.
So Jeong Park, Ji Yeon Baek, Shibo Wei, Jin Young Lee, Yuna Lee, Sang‐Hoon Lee, Il‐Young Jang, Hyuk Sakong, Hyun Ju Yoo, Hee‐Won Jung, Eunju Lee, Su Jung Kim, Yunju Jo, Kyunggon Kim, Dongryeol Ryu, Beom‐Jun Kim   +15 more
wiley   +1 more source

Temporal Metabolomics Profiling Reveals Liver Metabolic Control in Single and Repeated Exhaustive Exercise in Murine Models

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Temporal metabolomics profiling reveals divergent liver recovery trajectories between single and repeated exhausted exercise stress. Single exhaustive exercise (SEE) demonstrates transient metabolic perturbations resolving within 24 h. In contrast, repeated exhaustive exercise (REE) triggers sustained metabolic remodeling that persists beyond the ...
Jining Yang, Dawei Wang, Hui Shen, Yundong Xia, Hedong Lang, Wenxin Zhou, Long Yi, Mantian Mi   +7 more
wiley   +1 more source

Emerging roles of microRNAs and other non-coding transcriptome in muscular dystrophies. [PDF]

Inflamm Regen
Abdelrehim FG, Sadek Z, Fahim SA, El-Ekiaby N, Abdelaziz AI, Fawzy IO.   +5 more
europepmc   +1 more source