Results 161 to 170 of about 2,049,707 (290)

Satellite DNA Genomics: The Ongoing Story. [PDF]

Int J Mol Sci
Garrido-Ramos MA, Plohl M, Šatović-Vukšić E.   +2 more
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

Advanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua, Shuang Pang, Ang Li, Zonghao Hu, Honghui Wu, Shuhan Zhang, Yi Fan, Yi Wu, Wei Yang, Yachao Zhao, Yupeng Guan, Baoming Ji, Deliang Kong, Yong Zhao, Anton A. Goncharov, Anastasia Yu. Korotkevich, Rong Mao, Yang Zhang, Ximei Zhang   +18 more
wiley   +1 more source

Generation of alphoid DNA probes for fluorescence in situ hybridization using the polymerase chain reaction [PDF]

, 1994
Dunham, Ian, Cremer, Thomas, Featherstone, Terry, Lengauer, Christoph   +3 more
core   +1 more source

Satellite DNA evolution in two holocentric species of Edessa true bugs (Hemiptera: Pentatomidae) with unusually high heterochromatin abundance. [PDF]

Chromosome Res
Calegari LM, Milani D, Bardella VB, Hickmann F, Cabral-de-Mello DC.   +4 more
europepmc   +1 more source

Fast satellite DNA evolution in Nothobranchius annual killifishes. [PDF]

Chromosome Res, 2023
Voleníková A, Lukšíková K, Mora P, Pavlica T, Altmanová M, Štundlová J, Pelikánová Š, Simanovsky SA, Jankásek M, Reichard M, Nguyen P, Sember A.   +11 more
europepmc   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

Extracellular Alpha-Satellite DNA in Human Plasma as a Candidate Biomarker for Bladder Cancer Detection: Preliminary Evidence Using Digital PCR. [PDF]

Int J Mol Sci
Santini N, Procino A, Ljubić S, Đermić D, Ugarković Đ, Feliciello I.   +5 more
europepmc   +1 more source

Alpha Satellite DNA in Targeted Drug Therapy for Prostate Cancer. [PDF]

Int J Mol Sci, 2023
Feliciello I, Ugarković Đ.
europepmc   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source