DNA Environment of Centromeres and Non-Homologous Chromosomes Interactions in Mouse
Cells, 2021 Although the pericentromeric regions of chromosomes that are enriched in tandemly repeated satellite DNA represent a significant part of eukaryotic genomes, they remain understudied, which is mainly due to interdisciplinary knowledge gaps. Recent studies
Victor Spangenberg +5 more
doaj +1 more source
Epigenetic regulation of genes mediated by satellite DNA [PDF]
, 2016 Satellite DNA is a highly repetitive DNA, organized in long tandem arrays, located in the heterochromatic regions of chromosomes. Repeats of satellite DNAs can be excised from their heterochromatin loci and integrate into euchromatin.
Durdica Ugarkovic +2 more
core
Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]
, 1988 A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask +39 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Chromosomal Differentiation of Deschampsia (Poaceae) Based on Four Satellite DNA Families
Frontiers in Genetics, 2021 Diverse families of satellite DNA (satDNA) were detected in heterochromatin regions of Deschampsia. This kind of repetitive DNA consists of tandem repeat sequences forming big arrays in genomes, and can contribute to lineages differentiation.
María Laura González +2 more
doaj +1 more source
Dispersed satellite DNA elements and their effect on gene expression [PDF]
, 2013 Different from dispersed transposable elements whose role in evolution of gene regulation was investigated in diverse model organism, influence of satellites DNA on gene regulation was not investigated till now.
Akrap, Ivana +4 more
core
Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]
, 2015 Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng +5 more
core +3 more sources
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Satellite DNA Modulates Gene Expression in the Beetle Tribolium castaneum after Heat Stress. [PDF]
PLoS Genetics, 2015 Non-coding repetitive DNAs have been proposed to perform a gene regulatory role, however for tandemly repeated satellite DNA no such role was defined until now.
Isidoro Feliciello +2 more
doaj +1 more source
Protective role of γ ⁃ tocotrienol on muscle satellite cells of Duchenne muscular dystrophy in mice
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Objective To investigate the damage of skeletal muscle satellite cells in Duchenne muscular dystrophy (DMD) and the protective effect of γ⁃tocotrienol (GT3) on muscle satellite cells in DMD knockout mice.
YANG Shuo +5 more
doaj +1 more source