Results 61 to 70 of about 1,659,099 (259)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Ferromagnetism in the Highly-Correlated Hubbard Model
, 2010 The Hubbard model with strong correlations is treated in the many-electron representation of Hubbard's operators. The regions of stability of saturated and non-saturated ferromagnetism in the n-U plane for the square and simple cubic lattices are ...
Irkhin, V. Yu., Zarubin, A. V.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Maximal determinants and saturated D-optimal designs of orders 19 and 37 [PDF]
, 2011 A saturated D-optimal design is a {+1,-1} square matrix of given order with maximal determinant. We search for saturated D-optimal designs of orders 19 and 37, and find that known matrices due to Smith, Cohn, Orrick and Solomon are optimal.
Brent, Richard P. +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
STUDY REGARDING THE DESTABILIZATION OF STABLE EMULSIONS FROM SUPLAC AREA
Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2016 Emulsions from the wells in the Suplac area create great difficulties in removing water due to their specifications. A complex study was conducted in order to eliminate water from emulsions using alkaline-surfactants.
IULIANA VERONICA GHEŢIU +2 more
doaj
Foam used during EPB tunnelling in saturated sand, parameters determining foam consumption [PDF]
, 2012 The amount of foam injected during drilling with an EPB-shield in saturated sand is quite often based on experience and/or empiric relations. A method is presented in to calculate the amount of foam needed to create a muck with limited or no grain stress.
Bezuijen, Adam
core +1 more source
, 1999 The notion of a completely saturated packing [Fejes Toth, Kuperberg and Kuperberg, Highly saturated packings and reduced coverings, Monats. Math. 125 (1998) 127-145] is a sharper version of maximum density, and the analogous notion of a completely ...
Fejes Tóth +4 more
core +3 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Effects of Harvest Times on the Fatty Acids Composition of Rose Hip (Rosa sp.) Seeds
Turkish Journal of Agriculture: Food Science and Technology, 2017 This study was conducted to determine the change of fatty acids ratios of some rose hip species seeds in different harvest times. Seeds of five genotypes belonging to rose hip species (Rosa sp.) were used in the study.
Mehmet Güneş +3 more
doaj +1 more source