Results 81 to 90 of about 814,152 (292)
EFSA Journal, 2011 The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 61 flavouring substances in the Flavouring Group Evaluation 10, Revision 2, using the Procedure in Commission ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Getting Saturated with Induction
, 2022 Induction in saturation-based first-order theorem proving is a new exciting direction in the automation of inductive reasoning. In this paper we survey our work on integrating induction directly into the saturation-based proof search framework of first-order theorem proving.
Márton Hajdú +4 more
openaire +4 more sources
Electrophilic substitution at a saturated carbon atom /
, 1973 "All chapters in this volume have been written by M.H. Abraham"--Page vi.Includes bibliographical references and index.The formation and reactions of carbanions -- Mechanisms of electrophilic substitution at saturated carbon -- The unimolecular mechanism,
Bamford, C. H. +2 more
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Discrete MathematicsA graph $G$ is called $C_k$-saturated if $G$ is $C_k$-free but $G+e$ not for any $e\in E(\overline{G})$. The saturation number of $C_k$, denoted $sat(n,C_k)$, is the minimum number of edges in a $C_k$-saturated graph on $n$ vertices. Finding the exact values of $sat(n,C_k)$ has been one of the most intriguing open problems in extremal graph theory.
Yongxin Lan +3 more
openaire +3 more sources
Noise suppression of incoherent light using a gain-saturated SOA: implications for spectrum-sliced WDM systems [PDF]
, 2005 In this paper, we present an experimental and numerical study of semiconductor optical amplifier (SOA)-based noise suppression and its relevance to high-channel-density spectrum sliced wavelength-division-multiplexed systems. We show that the improvement
Ibsen, M +14 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source