Results 61 to 70 of about 1,669,701 (279)
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
, 2011 Bose-Einstein condensation is unique among phase transitions between different states of matter in the sense that it occurs even in the absence of interactions between particles.
C. Pethick +10 more
core +1 more source
The mechanical resistance of saturated stones [PDF]
, 2010 This paper aims at investigating the effect of the presence of water on the mechanical resistance of stones. The presence of water, connected to the intrinsic properties of the stone (mineralogical composition, fabric, texture, etc.) and to the ...
Marini P, Bellopede R
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Delving deeper into color space [PDF]
, 2018 So far, color-naming studies have relied on a rather limited set of color stimuli. Most importantly, stimuli have been largely limited to highly saturated colors.
Douven, Igor, Jraissati, Yasmina
core
Ferromagnetism in the Highly-Correlated Hubbard Model
, 2010 The Hubbard model with strong correlations is treated in the many-electron representation of Hubbard's operators. The regions of stability of saturated and non-saturated ferromagnetism in the n-U plane for the square and simple cubic lattices are ...
Irkhin, V. Yu., Zarubin, A. V.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Foam used during EPB tunnelling in saturated sand, parameters determining foam consumption [PDF]
, 2012 The amount of foam injected during drilling with an EPB-shield in saturated sand is quite often based on experience and/or empiric relations. A method is presented in to calculate the amount of foam needed to create a muck with limited or no grain stress.
Bezuijen, Adam
core +1 more source