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Background: In July 2013, the Philippines’ Event-Based Surveillance & Response Unit received a paralytic shellfish poisoning (PSP) report from Tarangnan, Western Samar.
Paola Katrina Ching +4 more
doaj +1 more source
A Stereocontrolled Synthesis of (+)-Saxitoxin [PDF]
A concise stereoselective total synthesis of (+)-saxitoxin is described. A silver(I)-initiated hydroamination cascade constructs the bicyclic guanidinium ion core from a alkynyl bisguanidine. This sequence creates two C-N bonds, one C-O bond, and three rings and forms a single stereoisomer in a single synthetic transformation.
Vasudev R, Bhonde, Ryan E, Looper
openaire +2 more sources
Bacterial Production of Saxitoxin
A bacterium was isolated from the homogenate of Protogonyaulax tamarensis cells cultured in T1 medium containing antibiotics. The culture broth after centrifugation, to remove the cells, and the bacterial cells contained a toxin that could kill mice with signs similar to those of poisoning by paralytic shellfish toxins or tetrodotoxin. The toxin in the
Masaaki KODAMA +2 more
openaire +2 more sources
Integrating scFv into xMAP Assays for the Detection of Marine Toxins
Marine toxins, such as saxitoxin and domoic acid are associated with algae blooms and can bioaccumulate in shell fish which present both health and economic concerns.
Lisa C. Shriver-Lake +6 more
doaj +1 more source
Characterization of Benzoyl Saxitoxin Analogs from the Toxigenic Marine Dinoflagellate Gymnodinium catenatum by Hydrophilic Interaction Liquid Ion-Chromatography-Tandem Mass Spectrometry [PDF]
The chain-forming marine dinoflagellate Gymnodinium catenatum Graham has a remarkable capacity to produce a wide array of neurotoxic alkaloids associated with Paralytic Shellfish Poisoning (PSP). More than a decade ago, a completely new group of benzoyl
Band-Schmidt, Christine J. +5 more
core +1 more source
Sophisticated sperm allocation in male fowl [PDF]
When a female is sexually promiscuous, the ejaculates of different males compete for the fertilization of her eggs; the more sperm a male inseminates into a female, the more likely he is to fertilize her eggs.
Pizzari, T. +4 more
core +1 more source
Guanadinium toxins and their interactions with voltage-gated sodium ion channels [PDF]
Guanidinium toxins, such as saxitoxin (STX), tetrodotoxin (TTX) and their analogs, are naturally occurring alkaloids with divergent evolutionary origins and biogeographical distribution, but which share the common chemical feature of guanidinium ...
Cembella, Allan, Duran, Lorena
core +2 more sources
The envenomation of general physiology throughout the last century. [PDF]
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core +1 more source
Previous studies of recreational waters and blue-green algae supplements (BGAS) demonstrated co-occurrence of Aphanizomenon flos-aquae (AFA) and cyanotoxins, presenting exposure risk.
Amber Lyon-Colbert +2 more
doaj +1 more source
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart +7 more
wiley +1 more source

