Results 21 to 30 of about 1,214 (139)

Simultaneous Multiclass Analysis of Cyanotoxins in Cyanobacterial Samples Using Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

open access: yesJ Sep Sci
ABSTRACT The proliferation of cyanobacteria can result in algal blooms, which may cause environmental and biological harm due to the production and release of secondary metabolites, or cyanotoxins, into the affected waterway. Cyanobacteria can produce multiple classes of cyanotoxins; therefore, to understand the full toxic load of algal blooms, it is ...
Bergin R   +3 more
europepmc   +2 more sources

An Electrochemical Ti3C2Tx Aptasensor for Sensitive and Label-Free Detection of Marine Biological Toxins

open access: yesSensors, 2021
Saxitoxin (STX) belongs to the family of marine biological toxins, which are major contaminants in seafood. The reference methods for STX detection are mouse bioassay and chromatographic analysis, which are time-consuming, high costs, and requirement of ...
Najeeb Ullah   +6 more
doaj   +1 more source

4-Aminopyridine Reverses Saxitoxin (STX)- and Tetrodotoxin (TTX)-Induced Cardiorespiratory Depression in Chronically Instrumented Guinea Pigs [PDF]

open access: yesFundamental and Applied Toxicology, 1997
The extent to which cardiorespiratory infirmity and other sublethal effects of saxitoxin (STX) and tetrodotoxin (TTX) can be reversed by 4-aminopyridine (4-AP) was investigated in guinea pigs chronically instrumented for the concurrent electrophysiological recordings of electrocorticogram (ECoG), diaphragmatic electromyogram (DEMG), Lead II ...
F C, Chang   +4 more
openaire   +2 more sources

Synthesis of Saxitoxin Biosynthetic Intermediates: Reveal the Mechanism for Formation of its Tricyclic Skeleton in Biosynthesis. [PDF]

open access: yesChem Asian J
Saxitoxin biosynthetic intermediate 7 and its 6‐epimer (10) along with 14 were synthesized from 13 in a single step, probably via aza‐Michael addition reaction. Compounds 7 and 10 were identified in the toxin‐producing cyanobacterium Dolichospernum circinale (TA04).
Hirozumi R   +8 more
europepmc   +2 more sources

Electrophysiological Evaluation of Pacific Oyster (Crassostrea gigas) Sensitivity to Saxitoxin and Tetrodotoxin

open access: yesMarine Drugs, 2021
Pacific oysters (Crassostrea gigas) may bio-accumulate high levels of paralytic shellfish toxins (PST) during harmful algal blooms of the genus Alexandrium. These blooms regularly occur in coastal waters, affecting oyster health and marketability.
Floriane Boullot   +5 more
doaj   +1 more source

Behavioral alterations induced by repeated saxitoxin exposure in drinking water

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2016
Background Blooms of the saxitoxin-producing cyanobacterium Cylindrospermopsis raciborskii have been contaminating drinking water reservoirs in Brazil for many years.
Felipe Diehl   +4 more
doaj   +1 more source

Toxicogenomic Effects of Dissolved Saxitoxin on the Early Life Stages of the Longfin Yellowtail (Seriola rivoliana)

open access: yesMarine Drugs, 2023
Harmful algal blooms (HABs) can produce a variety of noxious effects and, in some cases, the massive mortality of wild and farmed marine organisms. Some HAB species produce toxins that are released into seawater or transferred via food webs (particulate ...
Colleen Guinle   +4 more
doaj   +1 more source

Facile and Cost-Effective Detection of Saxitoxin Exploiting Aptamer Structural Switching

open access: yesFood Technology and Biotechnology, 2015
A simple method to detect saxitoxin (STX), one of the main components of the paralytic shellfish poison from red tide, has been developed. By using a next generation dye for double-stranded DNA we were able to differentiate fluorescence from STX-binding ...
Karol Alfaro   +3 more
doaj   +1 more source

Gustatory Detection of Tetrodotoxin and Saxitoxin, and Its Competitive Inhibition by Quinine and Strychnine in Freshwater Fishes

open access: yesMarine Drugs, 2011
Fish detect extremely low levels of marine toxins tetrodotoxin (TTX) and saxitoxin (STX) via the specialized gustatory receptor(s). Physiological and pharmacological studies show that receptor(s) for TTX and STX are distinct from those which detect ...
Toshiaki J. Hara
doaj   +1 more source

The cyanobacterial saxitoxin exacerbates neural cell death and brain malformations induced by Zika virus.

open access: yesPLoS Neglected Tropical Diseases, 2020
The northeast (NE) region of Brazil commonly goes through drought periods, which favor cyanobacterial blooms, capable of producing neurotoxins with implications for human and animal health.
Carolina da S G Pedrosa   +17 more
doaj   +1 more source

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