Electroanalysis, 2016 AbstractA miniaturized potentiometric saxitoxin sensor on graphene nanosheets with incorporated lipid films and Anti‐STX, the natural saxitoxin receptor, immobilized on the stabilized lipid films is described in the present paper. An adequate selectivity for detection over a wide range of toxin concentrations, fast response time of ca.
Bratakou, S. +5 more
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A comprehensive study on freshwater pufferfish Pao baileyi: profiles of toxin possession, accumulation, and uptake [PDF]
Frontiers in Veterinary ScienceFreshwater pufferfish, primarily belonging to the genus Pao, constitute an important branch in the family Tetraodontidae. Toxic freshwater pufferfish contain saxitoxin (STX) but lack tetrodotoxin (TTX), which is commonly found in marine pufferfish. Here,
Hongchen Zhu, Hongchen Zhu, Hongchen Zhu
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Marine Drugs, 2011 Fish detect extremely low levels of marine toxins tetrodotoxin (TTX) and saxitoxin (STX) via the specialized gustatory receptor(s). Physiological and pharmacological studies show that receptor(s) for TTX and STX are distinct from those which detect ...
Toshiaki J. Hara
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Artificial Intelligence (AI) in Saxitoxin Research: The Next Frontier for Understanding Marine Dinoflagellate Toxin Biosynthesis and Evolution [PDF]
ToxinsSaxitoxin (STX) is one of the most potent marine neurotoxins, produced by several species of freshwater cyanobacteria and marine dinoflagellates. Although omics-based approaches have advanced our understanding of STX biosynthesis in recent decades, the ...
Buhari Lawan Muhammad +4 more
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Development of a Sandwich-Type sxtA4 Electrochemical Biosensor for Proactive Environmental Monitoring of STX-Producing Microalgae [PDF]
BiosensorsSaxitoxin (STX), produced by certain harmful algal bloom (HAB) species, bioaccumulates through the food chain and can cause paralytic toxicity in humans, potentially resulting in fatal outcomes.
Hyunjun Park +7 more
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The cyanobacterial saxitoxin exacerbates neural cell death and brain malformations induced by Zika virus. [PDF]
PLoS Neglected Tropical Diseases, 2020 The northeast (NE) region of Brazil commonly goes through drought periods, which favor cyanobacterial blooms, capable of producing neurotoxins with implications for human and animal health.
Carolina da S G Pedrosa +17 more
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Toxins, 2019 Saxitoxin (STX) and its analogues, the potent voltage-gated sodium channel blockers, are biosynthesized by freshwater cyanobacteria and marine dinoflagellates.
Takashi Minowa +4 more
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Rapid Detection of Saxitoxin Using a Nucleic Acid Aptamer Biosensor Based on Graphene Oxide as a Fluorescence Quencher [PDF]
ToxinsSaxitoxin (STX) is a toxin with paralyzing and lethal properties, necessitating the development of a simple analytical method. This study developed a nucleic acid aptamer biosensor using graphene oxide (GO) as a fluorescence quencher for STX detection ...
Yi Jiao +8 more
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Transcriptomic insights into polyketides and toxin biosynthesis genes in freshwater dinoflagellates [PDF]
Scientific ReportsFreshwater dinoflagellates are typically considered non-toxic, and their polyketides and toxin biosynthesis genes are largely unexplored. Here, we generated and analyzed the transcriptome of freshwater dinoflagellate Palatinus apiculatus and compared it ...
Buhari Lawan Muhammad +3 more
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Saxitoxin potentiates human neuronal cell death induced by Zika virus while sparing neural progenitors and astrocytes [PDF]
Scientific ReportsThe Zika virus (ZIKV) epidemic declared in Brazil between 2015 and 2016 was associated with an increased prevalence of severe congenital malformations, including microcephaly.
Leticia R. Q. Souza +10 more
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