Results 61 to 70 of about 209,142 (219)

Evolving Strategies and Materials for Scaffold Development in Regenerative Dentistry

Applied Sciences
Regenerative dentistry has experienced remarkable advancement in recent years. The interdisciplinary discoveries in stem cell applications and scaffold design and fabrication, including novel techniques and biomaterials, have demonstrated immense ...
Michal Gašparovič, Petra Jungová, Juraj Tomášik, Bela Mriňáková, Dušan Hirjak, Silvia Timková, Ľuboš Danišovič, Marián Janek, Ľuboš Bača, Peter Peciar, Andrej Thurzo   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Gum Arabic: A Commodity with Versatile Formulations and Applications

Nanomaterials
Gum Arabic (GA), or acacia gum, refers to the dried exudate produced by certain Acacia trees. GA is composed mainly of a mixture of polysaccharides and glycoproteins, with proportions that can slightly differ from one species to another.
Shaymaa A. Mohamed, Asmaa M. Elsherbini, Heba R. Alrefaey, Kareem Adelrahman, Alshaimaa Moustafa, Nishal M. Egodawaththa, Kaitlyn E. Crawford, Nasri Nesnas, Sally A. Sabra   +8 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Decellularization techniques: unveiling the blueprint for tracheal tissue engineering

Frontiers in Bioengineering and Biotechnology
Certain congenital or acquired diseases and defects such as tracheo-oesophageal fistula, tracheomalacia, tracheal stenosis, airway ischemia, infections, and tumours can cause damage to the trachea.
Keisha T. Gomes, Palla Ranga Prasad, Jagnoor Singh Sandhu, Jagnoor Singh Sandhu, Ashwini Kumar, Naveena A. N. Kumar, N. B. Shridhar, Bharti Bisht, Manash K. Paul, Manash K. Paul   +9 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Novel and rapid analytical platform development enabled by advances in 3D printing

Frontiers in Analytical Science
3-Dimensional (3D) printing technology has greatly facilitated the recent advancements in science and engineering that benefit many aspects of scientific investigation, with examples including disease diagnostics, dentistry, aerospace, and fundamental ...
Alexander S. Malinick, Cole P. Ebel, Daniel D. Stuart, Santino N. Valiulis, Victor A. Hanson, Quan Cheng   +5 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Optimization of Bioinspired Scaffolds to Enhance Cell Viability and Enable Tissue Growth

Proceedings
The construction of artificial biological tissues presents complex interdisciplinary challenges, requiring the convergence of knowledge from materials science, biophysics, biology, design, and related fields.
Jackeline de Oliveira Riqueira, Danilo Barbosa Liarte, Silvia Lenyra Meirelles Campos Titotto   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source