Results 121 to 130 of about 11,276 (233)

Predictors of Mortality among Under-five Children Hospitalized with Severe Community-acquired Pneumonia. A Retrospective Observational Study

Journal of Medicine in Scientific Research
Background Severe community-acquired pneumonia (SCAP) remains a critical public health issue and a leading cause of childhood mortality and morbidity, especially in developing countries.
Marwa Taha
doaj   +1 more source

Chronic Senolytic Treatment and/or Aerobic Exercise Reduce Senescence and Improve Myocardial Function During Aging in the Heart

Aging Cell, Volume 25, Issue 10, October 2026.
Middle aged mice (12‐months‐old) administered senolytics and/or aerobic exercise for 9 months showed a significantly lower accumulation of senescent cardiomyocytes and improved myocardial function compared to mice aged naturally, independent of changes to the SASP.
Ryan T. Bevington, Amanda L. Johnson, Briana L. Hockey, Val A. Fajardo, Gianni Parise   +4 more
wiley   +1 more source

How digital influencer content and characteristics influence Generation Y persuasiveness and purchase intention

Tourism & Management Studies
This paper aims to understand the effect of content and digital influencer characteristics on their persuasiveness ability and Generation Y's resulting brand attitudes and purchase intentions (Millennials).
Maria Antónia Rodrigues , Maria Amélia Carvalho , Luciana Oliveira , Andreia Barbosa   +3 more
doaj  

The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis

Endocrinology and Metabolism, 2017
Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance, obesity, and dyslipidemia. NAFLD encompasses a wide range of states from the simple accumulation of triglycerides in the hepatocytes to serious states accompanied by inflammation and fibrosis in the liver.
openaire   +3 more sources

An Acidic Tubulointerstitial Microenvironment Delays Cell‐Cycle Progression in Proximal Tubule Cells and Fibroblasts and Synergizes With Lactate to Drive Phenotypic Alterations

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz, Virginie Dubourg, Lea Schaude, Natalie Schröder, Eva Janßen, Isabelle Görlich, Stefanie Ruhs, Michael Kopf, Michael Gekle   +8 more
wiley   +1 more source

Challenges and Opportunities for Layered Double Perovskite Solar Cells

Solar RRL, Volume 10, Issue 17, 15 September 2026.
Layered lead‐free double perovskites suffer from intrinsic and extrinsic limitations that hinder high photovoltaic performance. This review identifies key challenges, including unfavorable band structures, strong self‐trapping, defect‐induced recombination, processing‐induced inhomogeneity, and device‐level mismatches.
Krishnaiah Mokurala, Marija Mrkonjić, Ceylan Doyranli, Jovana V. Milić, Mohammad Reza Golobostanfard   +4 more
wiley   +1 more source

SCAP recruits IRF3 onto the STING signalosome.

, 2016
(A) The indicated plasmids with Flag tag were respectively transfected into HEK293T cells along with Myc-tagged SCAP. Cell lysates were immunoprecipitated with an anti-Myc antibody and immunoblotted with indicated antibodies.
Xing Liu (221084), Heng Liu (293917), Ye Cui (2273386), Chen Wang (88408), Peng Zhang (2071), Qiang Wang (32383), Lulu Huang (469776), Senlin Li (391558), Huansha Yu (540366), Yijun Tang (540365), Wei Chen (23863)   +10 more
core   +1 more source

Scap-Exos Ameliorate Sjogren’S Syndrome By Promoting Tregs Differentiation

International Dental Journal
Aim or purpose: To investigate the effects of stem cells from apical papilla-derived exosomes (SCAP-Exos) on ameliorating Sjogren’s syndrome (SS) and its underlying mechanism of promoting CD4+ T cells differentiation into regulatory T cells (Tregs ...
Aochen Wang, Liu Cao
doaj   +1 more source

Preliminary results of a multicenter study on the use of pathogenetic therapy in patients with severe community-acquired pneumonia depending on the sepsis phenotype

Журнал инфектологии
Increasing the effectiveness of intensive sepsis therapy is possible only if a personalized approach is provided with the identification of phenotypes.The aim of the study was to evaluate the outcomes of blood purification (BP) methods and ...
E. Z. Shamsutdinova, D. A. Gusev, M. Yu. Kabanov, T. A. Sergeeva, R. R. Kasaev, V. I. Sakharov, V. S. Afonchikov, I. A. Ruslyakova   +7 more
doaj   +1 more source

Identification of SCAP in STING protein complex.

, 2016
(A and B) HEK293T cells were transfected with indicated plasmids. Twenty-four hours after transfection, cell lysates were immunoprecipitated with an anti-HA antibody (A, upper), an anti-Flag antibody (B, upper) or an anti-Myc antibody (A and B, lower ...
Xing Liu (221084), Heng Liu (293917), Ye Cui (2273386), Chen Wang (88408), Peng Zhang (2071), Qiang Wang (32383), Lulu Huang (469776), Senlin Li (391558), Huansha Yu (540366), Yijun Tang (540365), Wei Chen (23863)   +10 more
core   +1 more source