Results 111 to 120 of about 11,276 (233)

Mis-localization of SCAP impairs its antiviral function.

, 2016
(A) Schematic diagram of wild-type SCAP and its mis-localization mutants. (B) The indicated constructs were individually transfected into Hela cells and then stained with an anti-Flag antibody before imaged by confocal microscopy. The ER was stained with
Xing Liu (221084), Heng Liu (293917), Ye Cui (2273386), Chen Wang (88408), Peng Zhang (2071), Qiang Wang (32383), Lulu Huang (469776), Senlin Li (391558), Huansha Yu (540366), Yijun Tang (540365), Wei Chen (23863)   +10 more
core   +1 more source

Osteogenic differentiation and proliferation of apical papilla stem cells using nanoparticles of Neo MTA and bioactive glass

Saudi Dental Journal
Objective: The aim of this study was to evaluate the osteogenic differentiation ability and proliferation of apical papilla stem cells using nanoparticles of Neo MTA and bioactive glass.
H. Abdelaziz, Abeer H. Mahran, T. Elsewify   +2 more
doaj   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, Volume 13, Issue 55, 5 October 2026.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Advanced Simulation and Performance Optimization of Eco‐Friendly Bilayer Perovskite Solar Cell Using SCAPS‐1D

Applied Research, Volume 5, Issue 5, October 2026.
This article presents a SCAPS‐1D simulation study on a bilayer perovskite solar cell using non‐toxic, eco‐friendly absorbers CaZrS3 and FASnI3, in the configuration FTO/TiO2/CaZrS3/FASnI3/Spiro‐OMeTAD/Au. The optimized device achieves a power conversion efficiency of 23% and fill factor of 86%, outperforming single‐junction and unoptimized bilayer ...
Vivekanand Yadav, Satish Kumar Yadav, Ahmad Iqbal Ghafori, Nikita Singh, Rajendra Bahadur Singh, Jyotsna Singh   +5 more
wiley   +1 more source

Simvastatin Induces Apoptosis but Attenuates Migration in SCAPs

International Dental Journal
Simvastatin has emerged as having a promising role in controlling stem cell behaviours. This study aimed to evaluate the effects of simvastatin on the viability, growth, and migration of stem cells isolated from apical papillae (SCAPs) in vitro. SCAPs were isolated and characterised.
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Chatvadee Kornsuthisopon, Thanaphum Osathanon   +4 more
openaire   +3 more sources

Regenerative Endodontic Procedure in Mandibular First Molar: A Clinical Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Regenerative endodontic procedures (REPs) have emerged as a biologically based treatment modality for managing immature permanent teeth with necrotic pulp, offering the potential for continued root development and periapical healing. This case report describes the regenerative endodontic treatment of a necrotic, immature mandibular first molar
Sorour Saeedi, Ali Hamedi, Mani Mansouri, Iman Shiezadeh   +3 more
wiley   +1 more source

Validating SCAP as a Therapeutic Target for Colorectal Cancer [PDF]

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide with an increased prevalence in adults below 50 years old, highlighting the need to develop more therapeutic options.
Al-Naamani, Aisha Saleh Abdullah
core   +1 more source

A Reproducible MRI‐Based Pipeline for Longitudinal Tracking of Laser‐Assisted Bioprinted Cells in Three‐Dimensional Constructs

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Laser‐assisted bioprinting was used to deposit iron oxide‐labelled endothelial cells in predefined patterns onto SCAP‐seeded gelatin biopapers to assemble multilayer constructs of increasing thickness. T2*‐weighted MRI monitored constructs for up to 35 days.
Mina Medojević, Charles Handschin, Ayako Washio, Malou Lea, Laurence Dallet, Aleksandar Jakovljević, Emeline J. Ribot, Olivia Kérourédan   +7 more
wiley   +1 more source

Sterol Sensing by Two Luminal Loops in Scap

, 2014
SREBP cleavage-activating protein (Scap) is an endoplasmic reticulum (ER) membrane protein that controls cholesterol homeostasis by transporting SREBPs from the ER to the Golgi complex.
Zhang, Yinxin
core  

Hypoxia modulates the differentiation potential of stem cells of the apical papilla (SCAP)

, 2014
Introduction: Stem cells from the apical papilla (SCAP) are a population of mesenchymal stem cells likely involved in regenerative endodontic procedures, and of potential use as therapeutic agents in other tissues.
Bouzin, Caroline, Leprince, Julian, Viswanath, Aiswarya, Aiswarya Viswanath, ., des Rieux, Anne, Everard, Amandine, Cani, Patrice D., Vanacker, Julie, Diogenes, Anibal, Feron, Olivier, De Berdt, Pauline, Cani, Patrice D, Leprince, Julian Grégoire   +12 more
core   +1 more source