Results 1 to 10 of about 73,153 (262)

Scavenger receptor mediates systemic RNA interference in ticks. [PDF]

PLoS ONE, 2011
RNA interference is an efficient method to silence gene and protein expressions. Here, the class B scavenger receptor CD36 (SRB) mediated the uptake of exogenous dsRNAs in the induction of the RNAi responses in ticks.
Kyaw Min Aung, Damdinsuren Boldbaatar, Rika Umemiya-Shirafuji, Min Liao, Xuan Xuenan, Hiroshi Suzuki, Remil Linggatong Galay, Tetsuya Tanaka, Kozo Fujisaki   +8 more
doaj   +3 more sources

A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake1 [PDF]

Journal of Lipid Research, 1998
The class A macrophage scavenger receptors (SR-A) are macrophage-specific trimeric integral membrane glycoproteins that have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's ...
Peter J. Gough, David R. Greaves, Siamon Gordon   +2 more
doaj   +2 more sources

Toll-like receptor 4 and macrophage scavenger receptor 1 crosstalk regulates phagocytosis of a fungal pathogen [PDF]

Nature Communications, 2023
The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C.
Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva-Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May   +10 more
doaj   +2 more sources

Scavenger Receptor C1 Mediates Toxicity of Binary Toxin from Lysinibacillus sphaericus to Ag55 Cells [PDF]

Toxins
Lysinibacillus sphaericus harboring Binary (BinA and BinB) toxins is highly toxic against Anopheles and Culex mosquito larvae. The Anopheles Ag55 cell line is a suitable model for investigating the mode of Bin toxin action.
Qi Zhang, Gang Hua, Laramie Smith, Michael J. Adang   +3 more
doaj   +2 more sources

Class B scavenger receptor resists WSSV replication by recognizing the viral lipid molecule and promoting phagocytosis [PDF]

Journal of Virology
Class B scavenger receptors (SRBs) have been well-studied in bacteria-induced immune responses in invertebrates. However, the status of SRB-defending viruses remains unclear.
Yi-Heng Huang, Xin-Lu Guo, Meng-Ke Shan, Gui-Wen Yang, Hui-Ting Yang   +4 more
doaj   +2 more sources

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in Physiology, 2023
High levels of low density lipoprotein (LDL) cholesterol and low levels of high density lipoprotein (HDL) cholesterol are risk factors for cardiovascular disease. Mice that lack genes involved in the clearance of LDL from the bloodstream, such as the LDL
Mark T. Fuller, Mark T. Fuller, Omid Dadoo, Omid Dadoo, Ting Xiong, Ting Xiong, Pardh Chivukula, Pardh Chivukula, Melissa E. MacDonald, Samuel K. Lee, Samuel K. Lee, Richard C. Austin, Richard C. Austin, Suleiman A. Igdoura, Bernardo L. Trigatti, Bernardo L. Trigatti   +15 more
doaj   +1 more source

Lack of a direct role for macrosialin in oxidized LDL metabolism

Journal of Lipid Research, 2003
Murine macrosialin (MS), a scavenger receptor family member, is a heavily glycosylated transmembrane protein expressed predominantly in macrophage late endosomes. MS is also found on the cell surface where it is suggested, on the basis of ligand blotting,
Maria C. de Beer, Zhenze Zhao, Nancy R. Webb, Deneys R. van der Westhuyzen, Willem J.S. de Villiers   +4 more
doaj   +1 more source

Amino terminus of apolipoprotein B suffices to produce recognition of malondialdehyde-modified low density lipoprotein by the scavenger receptor of human monocyte-macrophages

Journal of Lipid Research, 1997
Malondialdehyde, a product of lipid peroxidation, produces threshold conversion of low density lipoprotein (LDL) to a form recognized by type I and type II scavenger receptors of monocyte-macrophages.
J Kreuzer, A L White, T J Knott, M L Jien, M Mehrabian, J Scott, S G Young, M E Haberland   +7 more
doaj   +1 more source

Insights into the ligand binding specificity of SREC‐II (scavenger receptor expressed by endothelial cells)

FEBS Open Bio, 2021
SREC‐II (scavenger receptor expressed by endothelial cells II) is a membrane protein encoded by the SCARF2 gene, with high homology to class F scavenger receptor SR‐F1, but no known scavenging function.
Catherine Wicker‐Planquart, Pascale Tacnet‐Delorme, Laurence Preisser, Samy Dufour, Yves Delneste, Dominique Housset, Philippe Frachet, Nicole M Thielens   +7 more
doaj   +1 more source

Factors regulating the activities of the low density lipoprotein receptor and the scavenger receptor on human monocyte-macrophages.

Journal of Lipid Research, 1981
Improved techniques of cell isolation resulted in 90 to 100 million monocytes from a single donor. Addition of low density lipoprotein (LDL) to to cultures of these cells resulted in the down regulation of LDL receptor activity.
A M Fogelman, M E Haberland, J Seager, M Hokom, P A Edwards   +4 more
doaj   +1 more source