Results 271 to 280 of about 2,493,460 (390)

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Targeting scavenger receptor class B type 1 with a bioinspired ligand induces apoptosis or ferroptosis in AML. [PDF]

Blood Neoplasia
Lin AY, Rink JS, Yang E, Small S, Gerber JJ, Zak TJ, Altman J, Abaza Y, Platanias LC, Gordon LI, Thaxton CS.   +10 more
europepmc   +1 more source

Scavenger Receptor Class B Type I Is a Plasma Membrane Cholesterol Sensor

Circulation Research, 2013
Sonika Saddar, V. Carrière, Wan-Ru Lee, Keiji Tanigaki, I. Yuhanna, Saj Parathath, E. Morel, M. Warrier, Janet K. Sawyer, Robert D. Gerard, Ryan E. Temel, J. Brown, M. Connelly, C. Mineo, P. Shaul   +14 more
semanticscholar   +1 more source

The Macrophage Scavenger Receptors

The Journal of Japan Atherosclerosis Society, 1990
Tatsuhiko KODAMA, Fumimaro TAKAKU, Akiyo MATSUMOTO, Hiroshige ITAKURA   +3 more
openaire   +2 more sources

CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils [PDF]

, 2002
Indra Sethy Coraci, Jens Husemann, Joan W. Berman, Christine Hulette, Jennifer Dufour, Gabriele K. Campanella, Andrew D. Luster, Samuel C. Silverstein, Joseph El Khoury   +8 more
openalex   +1 more source

cDC1 Subtype‐Specific In Vivo Targeting of Liposomes

Advanced Science, EarlyView.
Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf, Michael Fichter, Lin Jian, Felicia Schön, Carina Jung, Paul Schneider, Kai Speth, Ana Mateos‐Maroto, Volker Mailänder, Kaloian Koynov, Svenja Morsbach, Katharina Landfester   +11 more
wiley   +1 more source

High-density lipoprotein attenuates lipopolysaccharide-induced IL-1β activation via scavenger receptor class B type 1. [PDF]

J Lipid Res
Deng H, Liang WY, Chen L, Huang K, Mccallum R, Rensen PCN, Boyd JH, Trinder M, Brunham LR.   +8 more
europepmc   +1 more source

Recent Progress in Studies on Macrophage Scavenger Receptors

, 1992
A. Matsumoto, Hiroshige Itakura, Tatsuhiko Kodama, Yoshio Yazaki   +3 more
openalex   +2 more sources

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Macrophages Internalize Epithelial-Derived Extracellular Vesicles That Contain Ferritin via the Macrophage Scavenger Receptor 1 to Promote Inflammatory Bowel Disease. [PDF]

J Extracell Vesicles
Zhang W, Dong W, Cheng C, Zhao H, Liu Y, Zaydel K, Frech L, Xing Z, Zhu W, Zhou B, Li Y, Meyron-Holtz EG, Li K.   +12 more
europepmc   +1 more source