Results 41 to 50 of about 2,429,614 (417)
Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1
MicrobiologyOpen, 2019 The histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling.
Robert Fultz +9 more
doaj +1 more source
P2X7 as a scavenger receptor for innate phagocytosis in the brain
British Journal of Pharmacology, 2018 The P2X7 receptor has been widely studied for its ATP‐induced pro‐inflammatory effect, but in the absence of a ligand, P2X7 has a second function as a scavenger receptor, which is active in the development of the human brain.
B. Gu, J. Wiley
semanticscholar +1 more source
Homeostasis: A scavenger receptor for haemoglobin [PDF]
Current Biology, 2001 Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
openaire +3 more sources
SCARF1: a multifaceted, yet largely understudied, scavenger receptor
Inflammation Research, 2018 BackgroundAs is a prerequisite of belonging to the scavenger receptor super family, SCARF1 (scavenger receptor class F, member 1) is known to play a key role in the binding and endocytosis of a wide range of endogenous and exogenous ligands ...
Daniel A. Patten
semanticscholar +1 more source
Theranostics, 2017 Rheumatoid arthritis (RA) is a chronic autoimmune disorder implicated in multiple joint affection and even disability. The activated macrophages perform a predominant role in onset and persistence of RA.
Modi Yang +7 more
semanticscholar +1 more source
Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]
EMBO J 22, 18 (15/09/2003) 4656-65, 2007 Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv +1 more source
LRP: a multifunctional scavenger and signaling receptor [PDF]
Journal of Clinical Investigation, 2001 The LDL receptor–related protein (LRP) is larger than but structurally similar to other members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3). Whereas the LDL receptor, the founding member of this family, appears to act solely in lipoprotein metabolism, the LRP and other members of this family appear to have other ...
Joachim Herz, Dudley K. Strickland
openaire +2 more sources
Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission [PDF]
, 2010 Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission. In this study we use a novel infectious coculture system to examine these alternative modes of infection.
Balfe, Peter +12 more
core +4 more sources
The macrophage scavenger receptor CD163
Immunobiology, 2005 Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Fabriek, Babs O +2 more
openaire +4 more sources
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]
, 2009 Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H. +11 more
core +1 more source