A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism [PDF]
, 1997 Attilio Rigotti +5 more
openalex +1 more source
Accelerated Bone Healing via Electrical Stimulation
Advanced Science, EarlyView.Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun +4 more
wiley +1 more source
Topology of Scavenger Receptor Class B Type I (SR-BI) on Brush Border Membrane
Journal of Veterinary Science, 2002 Both hydropathy plot and in vitro translation results predict the topology of SR-BI; the receptor is an integral membrane protein of 509 amino acids, consisting of a short cytoplasmic N-terminus of 9 amino acids followed by a first transmembrane domain of 22 amino acids, the extracellular domain of 408 amino acids, the second transmembrane domain of 22
Mun Han Lee, Chang Hoon Han
openaire +3 more sources
LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinases⃞
Journal of Lipid Research, 2009 Intracellular signals elicited by LDLs are likely to play a role in the pathogenesis associated with increased LDL blood levels. We have previously determined that LDL stimulation of human skin fibroblasts, used as a model system for adventitial ...
Natasa Bulat +2 more
doaj
Structure and dynamics of dynorphin peptide and its receptor [PDF]
arXiv, 2019 Dynorphin is a neuropeptide involved in pain, addiction and mood regulation. It exerts its activity by binding to the kappa opioid receptor (KOP) which belongs to the large family of G-protein coupled receptors. The dynorphin peptide was discovered in 1975, while its receptor was cloned in 1993.
arxiv
Advanced Science, EarlyView.Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi +7 more
wiley +1 more source
Scavenger Receptor Class B, Type I-mediated [3H]Cholesterol Efflux to High and Low Density Lipoproteins Is Dependent on Lipoprotein Binding to the Receptor [PDF]
, 2000 Xiang-ju Gu +2 more
openalex +1 more source
From Lab to Life: Self‐Powered Sweat Sensors and Their Future in Personal Health Monitoring
Advanced Science, EarlyView.This review focuses on recent advances in self‐powered sweat sensors in personal health monitoring, including sweat sensors, energy harvesters, energy management, and their applications. It analyzes the difficulties and challenges in the research field of self‐powered sweat sensors and looks into the future direction of self‐powered sweat sensors from ...
Nan Gao +3 more
wiley +1 more source
C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake[S]
Journal of Lipid Research, 2011 Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake.
Ling Guo +4 more
doaj
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Advanced Science, EarlyView.Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang +5 more
wiley +1 more source