Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease [PDF]
Cells, 2020 The process of atherosclerosis leads to the formation of plaques in the arterial wall, resulting in a decreased blood supply to tissues and organs and its sequelae: morbidity and mortality.
Gary A. Cuthbert +4 more
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Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes [PDF]
Frontiers in Immunology, 2020 Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid +6 more
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Apoptotic cell recognition receptors and scavenger receptors. [PDF]
Immunol Rev, 2016 SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Penberthy KK, Ravichandran KS.
europepmc +5 more sources
Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa [PDF]
Ecology and Evolution, 2020 Functional kleptoplasty is a photosymbiotic relationship, in which photosynthetically active chloroplasts serve as an intracellular symbiont for a heterotrophic host.
Jenny Melo Clavijo +6 more
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Defective expression of scavenger receptors in celiac disease mucosa. [PDF]
PLoS ONE, 2014 Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage.
Maria Laura Cupi +13 more
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Macrophage Scavenger Receptor Class A [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 Abstract —In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Menno P.J. de Winther +3 more
openalex +4 more sources
Scavenger Receptors: Emerging Roles in Cancer Biology and Immunology. [PDF]
Adv Cancer Res, 2015 Scavenger receptors constitute a large family of evolutionally conserved protein molecules that are structurally and functionally diverse. Although scavenger receptors were originally identified based on their capacity to scavenge modified lipoproteins, these molecules have been shown to recognize and bind to a broad spectrum of ligands, including ...
Yu X +4 more
europepmc +5 more sources
Standardizing Scavenger Receptor Nomenclature [PDF]
The Journal of Immunology, 2014 Abstract Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens.
PrabhuDas, Mercy +14 more
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Scavenger receptor-BI is a receptor for lipoprotein(a) [PDF]
Journal of Lipid Research, 2013 Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ligand. Stable cell lines (HEK293 and HeLa) expressing human SR-BI were incubated with protein- or lipid-
Roger Kurlander +9 more
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Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
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