Results 11 to 20 of about 53,407 (301)

The evolution of the class A scavenger receptors [PDF]

BMC Evolutionary Biology, 2012
Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J, Meehan Conor J, Golding G Brian, McConkey Brendan J, E Bowdish Dawn M   +4 more
doaj   +5 more sources

Scavenger Receptors and Atherosclerosis

Biological Research, 2000
Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands ...
ATTILIO RIGOTTI
doaj   +7 more sources

Defective expression of scavenger receptors in celiac disease mucosa. [PDF]

PLoS ONE, 2014
Celiac disease (CD) is a gluten sensitive enteropathy characterized by a marked infiltration of the mucosa with immune cells, over-production of inflammatory cytokines and epithelial cell damage.
Maria Laura Cupi, Massimiliano Sarra, Daniela De Nitto, Eleonora Franzè, Irene Marafini, Ivan Monteleone, Giovanna Del Vecchio Blanco, Omero Alessandro Paoluzi, Davide Di Fusco, Paolo Gentileschi, Angela Ortenzi, Alfredo Colantoni, Francesco Pallone, Giovanni Monteleone   +13 more
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Scavenger receptors. [PDF]

Curr Biol, 2020
Scavenger receptors (SRs) are a large family of cell-surface receptors that are diverse in their structure and biological function and are divided into different classes. SRs can bind to a range of ligands and enhance the elimination of altered-self or non-self targets.
Alquraini A, El Khoury J.
europepmc   +4 more sources

Standardizing Scavenger Receptor Nomenclature [PDF]

The Journal of Immunology, 2014
Abstract Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a variety of ligands, including endogenous and modified host-derived molecules and microbial pathogens.
PrabhuDas, Mercy, Bowdish, Dawn, Drickamer, Kurt, Febbraio, Maria, Herz, Joachim, Kobzik, Lester, Krieger, Monty, Loike, John D., Means, Terry K., Moestrup, Soren K., Post, Steven, Sawamura, Tatsuya, Silverstein, Samuel C., Wang, Xiang-Yang, El Khoury, Joseph   +14 more
openaire   +3 more sources

Scavenger receptor-BI is a receptor for lipoprotein(a) [PDF]

Journal of Lipid Research, 2013
Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ligand. Stable cell lines (HEK293 and HeLa) expressing human SR-BI were incubated with protein- or lipid-
Roger Kurlander, Marcelo Amar, Xiao Ping Yang, Tatyana G. Vishnyakova, Boris L. Vaisman, Alan T. Remaley, Alexander V. Bocharov, Amy P. Patterson, Lewis C. Becker, Lita A. Freeman   +9 more
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Macrophage Scavenger Receptor Class A [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2000
Abstract—In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Menno P.J. de Winther, Ko Willems van Dijk, Louis M. Havekes, Marten H. Hofker   +3 more
openalex   +5 more sources

Apoptotic cell recognition receptors and scavenger receptors. [PDF]

Immunol Rev, 2016
SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Penberthy KK, Ravichandran KS.
europepmc   +5 more sources

Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria

Frontiers in Cellular and Infection Microbiology, 2021
Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo, Huiru Jing, Lei Yuan, Yanzhe Wang, Hui Xiao, Qian Zheng   +5 more
doaj   +1 more source

Scavenger receptors in atherosclerosis [PDF]

Current Opinion in Hematology, 1997
Membership in the broad family of scavenger receptors has grown significantly. Two new scavenger receptor receptors have been cloned (SR-BI and SR-CI) and a previously isolated integral membrane protein (CD36) has been found to possess lipoprotein binding properties that entitle it to be included in the family. The breadth of ligand recognition of this
openaire   +3 more sources