Results 21 to 30 of about 53,683 (320)
Scavenger receptors in atherosclerosis [PDF]
Current Opinion in Hematology, 1997 Membership in the broad family of scavenger receptors has grown significantly. Two new scavenger receptor receptors have been cloned (SR-BI and SR-CI) and a previously isolated integral membrane protein (CD36) has been found to possess lipoprotein binding properties that entitle it to be included in the family. The breadth of ligand recognition of this
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International Journal of Hypertension, 2010 Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen +7 more
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Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection. [PDF]
PLoS ONE, 2014 Staphylococcus aureus is a major human opportunistic pathogen responsible for a broad spectrum of infections ranging from benign skin infection to more severe life threatening disorders (e.g.
Charlène Blanchet +4 more
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Scavenger receptors in human airway epithelial cells: role in response to double-stranded RNA.
PLoS ONE, 2012 Scavenger receptors and Toll-like receptors (TLRs) cooperate in response to danger signals to adjust the host immune response. The TLR3 agonist double stranded (ds)RNA is an efficient activator of innate signalling in bronchial epithelial cells.
Audrey Dieudonné +8 more
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Deletion of the murine scavenger receptor CD68 [PDF]
Journal of Lipid Research, 2011 Scavenger receptors (ScRs) are a structurally unrelated family of receptors with the ability to bind modified low density lipoprotein (LDL) as well as a broad range of polyanionic ligands. CD68, whose expression is restricted to mononuclear phagocytes, is a unique ScR family member, owing to its lysosome associated membrane protein (LAMP)-like domain ...
Song, Li +2 more
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Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
Medicina, 2022 Background and Objectives: Cardiovascular (CV) risk is elevated in rheumatoid arthritis (RA). RA patient plasma causes pro-atherogenic derangements in cholesterol transport leading to macrophage foam cell formation (FCF).
Saba Ahmed +6 more
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Homeostasis: A scavenger receptor for haemoglobin [PDF]
Current Biology, 2001 Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
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Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection
Nature Communications, 2017 Scavenger receptors can function as pattern recognition receptors to sense infection. Here the authors show that, in response to worm and bacterial infection, scavenger receptor class A prevents nuclear localization of IRF5 and thereby drives M2 ...
Zhipeng Xu +15 more
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LRP: a multifunctional scavenger and signaling receptor [PDF]
Journal of Clinical Investigation, 2001 The LDL receptor–related protein (LRP) is larger than but structurally similar to other members of the LDL receptor gene family, an ancient family of endocytic receptors (1–3). Whereas the LDL receptor, the founding member of this family, appears to act solely in lipoprotein metabolism, the LRP and other members of this family appear to have other ...
Joachim Herz, Dudley K. Strickland
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