Results 31 to 40 of about 18,834 (279)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Bis{μ-2-[1-(2-Pyridylmethylimino)ethyl]phenolato}bis[azidocopper(II)]

Acta Crystallographica Section E, 2009
The title compound, [Cu2(C14H13N2O)2(N3)2], was synthesized by the reaction of Cu(NO3)2·3H2O with the Schiff base 2-[1-(2-pyridylmethylimino)ethyl]phenol (HL) in methanol–water solution, adding NaN3 as the bridging ligand.
Jun Zhang, Xiao-Dan Chen, Huai-Hong Zhang, Bai-Wang Sun   +3 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

CNSL green catalyst of sulfone-based Schiff base ligand and its metal(II) complexes: Antibacterial, anticancer and molecular docking studies

Results in Chemistry
Nowadays, the use of many organic solvents poses a serious threat to the atmosphere due to the release of toxic by-products. Therefore, the use of solvent-free green catalysts to solve this problem has brought about a significant change in the field of ...
C. Krishna Moorthy, T. Gomathi, M. Kannan, T. Mohana Priya   +3 more
doaj   +1 more source

Covalent Organic Frameworks for Photocatalytic CO2 Reduction: Metal Integration Principles, Strategies and Functions

Advanced Functional Materials, EarlyView.
Covalent organic frameworks (COFs) with metals have been recognized as versatile platforms for photocatalytic CO2 reduction (CO2PRR). Herein, an overview of metal integration strategies for COFs is systematically summarized. Regulatory mechanisms and structure–activity relationships between metal integration and COF‐based CO2PRR are emphasized.
Jie He, Minxian Zhang, Jinqiang Zhang, Hongqi Sun, Shaobin Wang, Xiaoguang Duan   +5 more
wiley   +1 more source

Eco-friendly synthesis of azo Schiff base ligand and its metal complexes: Anticancer, antidiabetic and antimicrobial activities

Mongolian Journal of Chemistry
Now a days Cancer, Diabetics and other diseases are become major issue of the society. Due to this synthesis of potential medicines against it is a major challenge to the researcher and hence Schiff base ligand became an attracting class of researcher ...
Kuldeep B. Sakhare, Kirti N. Sarwade, Yogesh N. Bharate, Mahadeo A Sakhare   +3 more
doaj   +1 more source

Spectral, Structural, and Antibacterial Study of Copper(II) Complex with N2O2 Donor Schiff Base Ligand and Its Usage in Preparation of CuO Nanoparticles

Journal of Chemistry, 2022
A new Schiff base complex, Cu(H2L)2 (H3L: 6,6′-((1E,1′E)-((azanediylbis(ethane-2,1-diyl))bis(azanylylidene))bis(methanylylidene))bis(2-methoxyphenol)), through the reaction of ligand H3L with Cu(NO3)2 3H2O, in the ratio of 2 : 1 in methanol solvent was ...
Afshin Saadat, Alireza Banaei, Patrick Mcardle, Rana Jafari   +3 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Synthesis of New Schiff Base Ligand and Its Complexes in The Presence of Some Transition Metal Ion and Evaluation of Their Antibacterial Properties

Medical Laboratory Journal, 2017
Background and objectives: Synthesis and characterization of several metal complexes (metal ions: Co2+, Ti4+ and Ce3+) of macroacyclic Schiff base ligand have been reported.
Taiebeh Tamoradi, Hamid Goudarziafshar, Somayeh Rashki, Fatemeh Katouzian, Firoozeh Chalabian   +4 more
doaj  

Green route for efficient synthesis of metal complexes of 4-bromo-2-((E)-((2-hydroxyphenyl)imino)methyl)-6-((E)-(3-nitrophenyl)diazenyl)phenol and its anti-hyperglycemia, anticancer and antimicrobial assessment [PDF]

Journal of the Serbian Chemical Society
The world is battling cancer and diabetes, prompting global research into effective drugs. Studies show coordination compounds, especially substituted salicylaldehydes, exhibit strong biological activity, which increases when treated with amines.
Sakhare Kuldeep B., Sarwade Kirti N., Joshi Hansaraj U., Sakhare Mahadeo A.   +3 more
doaj   +1 more source