Results 11 to 20 of about 80,911 (264)

Schistosoma mansoni.

Trends in Parasitology, 2020
Timothy J C Anderson, Egie E Enabulele
semanticscholar   +4 more sources

Booming Omics in Schistosoma [PDF]

Trends in Parasitology, 2021
Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al. and Wang et al. deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite ...
Le Govic, Yohann, Gourbal, Benjamin, Boissier, Jérôme   +2 more
openaire   +4 more sources

Morphological and genomic characterisation of the Schistosoma hybrid infecting humans in Europe reveals admixture between Schistosoma haematobium and Schistosoma bovis

PLoS Neglected Tropical Diseases, 2021
Schistosomes cause schistosomiasis, the world’s second most important parasitic disease after malaria in terms of public health and social-economic impacts.
J. Kincaid-Smith, A. Tracey, Ronaldo de Carvalho Augusto, I. Bulla, N. Holroyd, A. Rognon, O. Rey, C. Chaparro, A. Oleaga, S. Mas‐Coma, J. Allienne, C. Grunau, M. Berriman, J. Boissier, E. Toulza   +14 more
semanticscholar   +1 more source

Hybridized Zoonotic Schistosoma Infections Result in Hybridized Morbidity Profiles: A Clinical Morbidity Study amongst Co-Infected Human Populations of Senegal

Microorganisms, 2021
Hybridization of infectious agents is a major emerging public and veterinary health concern at the interface of evolution, epidemiology, and control.
C. Fall, S. Lambert, E. Léger, Lucy Yasenev, A. Garba, S. Diop, A. Borlase, S. Catalano, B. Faye, M. Walker, Mariama Sène, J. Webster   +11 more
semanticscholar   +1 more source

A novel, non-neuronal acetylcholinesterase of schistosome parasites is essential for definitive host infection

Frontiers in Immunology, 2023
Schistosomes are long-lived parasitic worms that infect >200 million people globally. The intravascular life stages are known to display acetylcholinesterase (AChE) activity internally as well as, somewhat surprisingly, on external tegumental ...
Patrick J. Skelly, Akram A. Da’dara
doaj   +1 more source

Circulating Anodic Antigen (CAA): A Highly Sensitive Diagnostic Biomarker to Detect Active Schistosoma Infections—Improvement and Use during SCORE

American Journal of Tropical Medicine and Hygiene, 2020
. The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was funded in 2008 to conduct research that would support country schistosomiasis control programs. As schistosomiasis prevalence decreases in many places and elimination is
P. Corstjens, C. de Dood, S. Knopp, Michelle N Clements, G. Ortu, I. Umulisa, E. Ruberanziza, U. Wittmann, T. Kariuki, P. LoVerde, W. Secor, Lydia S. Atkins, S. Kinung’hi, S. Binder, C. Campbell, D. Colley, G. V. van Dam   +16 more
semanticscholar   +1 more source

Concomitant Immunity and Worm Senescence May Drive Schistosomiasis Epidemiological Patterns: An Eco-Evolutionary Perspective

Frontiers in Immunology, 2020
In areas where human schistosomiasis is endemic, infection prevalence and egg output are known to rise rapidly through childhood, reach a peak at 8–15 years of age, and decline thereafter.
Julia C. Buck, Giulio A. De Leo, Giulio A. De Leo, Susanne H. Sokolow, Susanne H. Sokolow   +4 more
doaj   +1 more source

Impact of Different Mass Drug Administration Strategies for Gaining and Sustaining Control of Schistosoma mansoni and Schistosoma haematobium Infection in Africa

American Journal of Tropical Medicine and Hygiene, 2020
. This report summarizes the design and outcomes of randomized controlled operational research trials performed by the Bill & Melinda Gates Foundation–funded Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) from 2009 to 2019 ...

semanticscholar   +1 more source

Focal eosinophilic infiltration of the liver, benign or malignant?

Clinical Case Reports, 2021
Focal eosinophilic infiltration (FEI) of the liver shares imaging characteristics with malignant hepatic lesions but should be suspected when concomitantly observing eosinophilia. While in itself benign, the cause of FEI should be sought and treated.
Wouter Claeys, Anke Delie, Peter Smeets, Marie‐Angelique De Scheerder, Helena Degroote, Xavier Verhelst, Hans Van Vlierberghe, Anja Geerts   +7 more
doaj   +1 more source

Schistosome Vaccine Adjuvants in Preclinical and Clinical Research

Vaccines, 2014
There is currently no vaccine available for human use for any parasitic infections, including the helminth disease, schistosomiasis. Despite many researchers working towards this goal, one of the focuses has been on identifying new antigenic targets. The
Rachel Stephenson, Hong You, Donald P. McManus, Istvan Toth   +3 more
doaj   +1 more source