Results 11 to 20 of about 123,784 (291)
Schistosoma “Eggs-Iting” the Host: Granuloma Formation and Egg Excretion
Frontiers in Immunology, 2018 Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle involving infections of an aquatic snail intermediate host and a definitive ...
Christian Schwartz +3 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2020 BACKGROUND:Clinical observations and animal studies have suggested that Salmonella intestinal carriage is promoted by concurrent Schistosoma infection.
Lisette Mbuyi-Kalonji +13 more
doaj +2 more sources
Reduced efficacy of praziquantel against Schistosoma mansoniis associated with multiple rounds of mass drug administration [PDF]
Clinical Infectious Diseases, 2016 Background: Mass drug administration (MDA) with praziquantel is the cornerstone of schistosomiasis control in sub-Saharan Africa. The effectiveness of this strategy is dependent on the continued high efficacy of praziquantel; however, drug efficacy is ...
Cotton, James A. +6 more
core +5 more sources
Hybridisations within the genus Schistosoma: implications for evolution, epidemiology and control [PDF]
Parasitology, 2016 SUMMARYHybridization of parasites is an emerging public health concern in our changing world. Hybridization and introgression in parasites and pathogens can have major impacts on the host and the epidemiology and evolution of disease.
Leger, E, Webster, J P
core +2 more sources
Frontiers in Immunology, 2018 Studies on parasite-induced immunoregulatory mechanisms could contribute to the development of new therapies for inflammatory diseases such as type 2 diabetes (T2D), which is a chronic inflammatory disease characterized by persistent elevated glucose ...
Chun-Lian Tang +3 more
doaj +2 more sources
Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma‐Pulmonary Hypertension
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Inflammation underlies many forms of pulmonary hypertension (PH), including that resulting from Schistosoma infection, a major cause of PH worldwide.
Rahul Kumar +13 more
doaj +2 more sources
The Role of Type 2 Inflammation in Schistosoma-Induced Pulmonary Hypertension
Frontiers in Immunology, 2019 Approximately 5% of individuals chronically infected with Schistosoma mansoni develop pulmonary hypertension (PH). The disease is progressive and often fatal, and treatment options are palliative, not curative. Recent studies have unraveled major players
Claudia S. Mickael, Brian B. Graham
doaj +2 more sources
Booming Omics in Schistosoma [PDF]
Trends in Parasitology, 2021 Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al. and Wang et al. deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite ...
Le Govic, Yohann +2 more
openaire +4 more sources
Population Genetic Structure and Hybridization of Schistosoma haematobium in Nigeria
Pathogens, 2022 Background: Schistosomiasis is a major poverty-related disease caused by dioecious parasitic flatworms of the genus Schistosoma with a health impact on both humans and animals.
A. M. Onyekwere +6 more
semanticscholar +1 more source