Results 51 to 60 of about 78,832 (263)

Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins

European Journal of Organic Chemistry, EarlyView.
The synthesis of triterpenoid saponins bearing a Lewis‐X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin‐targeted therapeutic applications, are prepared through iterative and ...
Oscar Javier Gamboa Marin, Nitish Verma, Maude Cloutier, Charles Gauthier   +3 more
wiley   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

SCHISTOSOMIASIS, Hubungan Respon Imun dan Perubahan Patologi

Majalah Kedokteran Andalas, 2011
AbstrakSchistosomiasis merupakan suatu penyakit tropik yang disebabkan oleh cacing genus Schistosoma. Spesies yang dapat menginfeksi manusia antara lain Schistosoma mansoni, Schistosoma japonicum, Schistosoma mekongi, Schistosoma haematobium dan ...
Selfi Renita Rusjdi
doaj   +1 more source

Prevalence and Reinfection Rates of Schistosoma mansoni and Praziquantel Efficacy against the Parasite among Primary School Children in Sanja Town, Northwest Ethiopia

Journal of Parasitology Research, 2019
Background Schistosomiasis is among the most widespread chronic infections in the world. The magnitude of the infection may show variations across different areas with respect to time.
Eden Woldegerima, A. Bayih, Yalewayker Tegegne, Mulugeta Aemero, Ayalew Jejaw Zeleke   +4 more
semanticscholar   +1 more source

The Schistosoma Granuloma: Friend or Foe? [PDF]

Frontiers in Immunology, 2013
Infection of man with Schistosoma species of trematode parasite causes marked chronic morbidity. Individuals that become infected with Schistosomes may develop a spectrum of pathology ranging from mild cercarial dermatitis to severe tissue inflammation, in particular within the liver and intestines, which can lead to life threatening hepatosplenomegaly.
Hams E., Aviello G., Fallon P. G.
openaire   +7 more sources

Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase

Pest Management Science, EarlyView.
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier, David M Barber, Guido Bojack, Birgit Bollenbach‐Wahl, Luke Churchman, Uwe Döller, Tyler Fahrenhorst‐Jones, Jörg Freigang, Elmar Gatzweiler, Claudia Hartfiel, Caroline Hilmi, Yoann Huet, Bernd Laber, Gudrun Lange, Stephanie Lee, Virginie Lempereur, Marc Mosrin, Thomas Müller, China M Payne, Olaf Peters, Luka Posa, Shaun Rees, Anna M Reingruber, Jullien Rey, Jörg Tiebes, Karen Tilmant, Jens Frackenpohl   +26 more
wiley   +1 more source

Development of a laboratorial platform for diagnosis of schistosomiasis mansoni by PCR-ELISA

BMC Research Notes, 2018
Objective We developed a laboratorial platform to release a commercial platform used in the PCR-ELISA for the molecular diagnosis of schistosomiasis mansoni.
Carolina Senra, Luciana Inácia Gomes, Liliane Maria Vidal Siqueira, Paulo Marcos Zech Coelho, Ana Rabello, Edward Oliveira   +5 more
doaj   +1 more source

Alterations of the Mice Gut Microbiome via Schistosoma japonicum Ova-Induced Granuloma

Frontiers in Microbiology, 2019
Schistosomiasis, also called bilharziasis, is a neglected tropical disease induced by Schistosoma spp. that causes hundreds of millions of infections. Although Schistosoma ova-induced granulomas commonly cause inflammation, hyperplasia, ulceration, micro
Yanqing Zhao, Shuguo Yang, Bei Li, Wei Li, Jue Wang, Zongyun Chen, Jing Yang, Huabing Tan, Jian Li   +8 more
semanticscholar   +1 more source

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Neurogastroenterology &Motility, EarlyView.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

Hepatitis G Virus Infection in Patients with Hepatitis C

Journal of High Institute of Public Health, 2010
Hepatitis G virus (HGV) infection is a worldwide health problem causing acute and chronic non A- E hepatitis. Because HGV and hepatitis C virus (HCV) share same modes of transmission, co-infection with the two viruses is not uncommon especially among ...
Heba S. Selim, Mohamed A.El Barrawy, Osama N. Mohamed, Marwa S. Gamal El Din   +3 more
doaj   +1 more source