Results 61 to 70 of about 56,119 (295)

Post-translational processing of Schizosaccharomyces pombe YPT proteins.

Journal of Biological Chemistry, 1992
ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl, proteolytic trimming of AAX, and carboxyl-methylation. These modifications co-operate with palmitoylation of nearby sites or a polybasic region to target plasma membrane localization.
John F. Hancock, Anthony I. Magee, Erica Fawell, Chris Newman, Thomas Giannakouros, John Armstrong   +5 more
openaire   +3 more sources

The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]

, 2007
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton, al-Khodairy, Allshire, Allshire, Andrews, Apionishev, Branzei, Chakrabarti, Cheng, E.A. Outwin, Ekwall, F.-X. Ogi, F.Z. Watts, Grishchuk, Ho, Ho, Hoege, Hooker, J.C.-Y. Ho, Johnson, Kagey, Kahyo, L. Gardner, L.K. Boyd, M.A.M. Trickey, McDonald, Okubo, Pichler, Potts, Reindle, Sachdev, Schmidt, Sergeant, Shayeghi, Shin, Stelter, Strahl-Bolsinger, Tanaka, Taylor, Thon, Watts, Xhemalce, Xhemalce, Zhao, Zhao   +44 more
core   +2 more sources

N-Terminus Does Not Govern Protein Turnover of Schizosaccharomyces pombe CENP-A [PDF]

International Journal of Molecular Sciences, 2020
Centromere integrity underlies an essential framework for precise chromosome segregation and epigenetic inheritance. Although centromeric DNA sequences vary among different organisms, all eukaryotic centromeres comprise a centromere-specific histone H3 variant, centromeric protein A (CENP-A), on which other centromeric proteins assemble into the ...
Hwei Ling Tan, Ee Sin Chen, Ee Sin Chen, Yi Bing Zeng   +3 more
openaire   +3 more sources

Tandem affinity purification protocol for isolation of protein complexes from Schizosaccharomyces pombe

STAR Protocols, 2022
Summary: Many cellular processes require the activities of complex molecular machines composed of several protein subunits. Insights into these systems can be gained by isolation of protein complexes followed by in vitro analyses determining the identity,
Lubos Cipak, Tomas Selicky, Jan Jurcik, Ingrid Cipakova, Michaela Osadska, Veronika Lukacova, Peter Barath, Juraj Gregan   +7 more
doaj  

Inter-species complementation of the translocon beta subunit requires only its transmembrane domain. [PDF]

PLoS ONE, 2008
In eukaryotes, proteins enter the secretory pathway through the translocon pore of the endoplasmic reticulum. This protein translocation channel is composed of three major subunits, called Sec61alpha, beta and gamma in mammals. Unlike the other subunits,
Alexandre Leroux, Luis A Rokeach
doaj   +1 more source

The DNA damage checkpoint: A tale from budding yeast

Frontiers in Genetics, 2022
Studies performed in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have led the way in defining the DNA damage checkpoint and in identifying most of the proteins involved in this regulatory network, which turned out to have structural
Paolo Pizzul, Erika Casari, Marco Gnugnoli, Carlo Rinaldi, Flavio Corallo, Maria Pia Longhese   +5 more
doaj   +1 more source

Dependence of protein-induced lipid bilayer deformations on protein shape [PDF]

, 2022
Membrane proteins typically deform the surrounding lipid bilayer membrane, which can play an important role in the function, regulation, and organization of membrane proteins. Membrane elasticity theory provides a beautiful description of protein-induced lipid bilayer deformations, in which all physical parameters can be directly determined from ...
arxiv   +1 more source

Smc5/6 is required for repair at collapsed replication forks. [PDF]

, 2006
In eukaryotes, three pairs of structural-maintenance-of-chromosome (SMC) proteins are found in conserved multisubunit protein complexes required for chromosomal organization.
Ampatzidou, Eleni, Irmisch, Anja, Murray, Johanne M, O'Connell, Matthew J   +3 more
core   +3 more sources

The RNA Binding Protein Csx1 Promotes Sexual Differentiation in Schizosaccharomyces pombe

PLoS ONE, 2012
Sexual differentiation is a highly regulated process in the fission yeast Schizosaccharomyces pombe and is triggered by nutrient depletion, mainly nitrogen source. One of the key regulatory proteins in fission yeast sexual differentiation is the transcription factor Ste11.
Matia-González, Ana M., Sotelo, Jael, Rodríguez Gabriel, Miguel Ángel   +2 more
openaire   +9 more sources

Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition [PDF]

, 2013
Previously we identified Rrp1 and Rrp2 as two proteins required for the Sfr1/Swi5-dependent branch of homologous recombination (HR) in Schizosaccharomyces pombe.
Ahn, Akamatsu, Akamatsu, Akamatsu, Antony M. Carr, Cal-Bąkowska, Caspari, Craven, Doe, Doe, Dorota Dziadkowiec, Dupaigne, Dziadkowiec, Feng, Gareau, Haruta, Hecker, Hope, Hope, Ira, Jensen, Jia, Karol Kramarz, Karolina Kanik, Khasanov, Krogh, Kurokawa, Lambert, Lambert, Liu, Liu, Liu, Lorenz, Mankouri, McGlynn, Miyabe, Moreno, Morishita, Mullen, Mullen, Murray, New, Osman, Osterman, Piotr Wiśniewski, Prakash, Prudden, Raji, Rijkers, Say, Sebesta, Shinohara, Shinohara, Stewart, Sun, Sun, Sun, Sung, Symington, Thacker, Tsubouchi, Tsutsui, Uzunova, Win, Yuan   +64 more
core   +1 more source