Results 81 to 90 of about 56,119 (295)

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, EarlyView.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Processes Controlling the Contractile Ring during Cytokinesis in Fission Yeast, Including the Role of ESCRT Proteins

Journal of Fungi
Cytokinesis, as the last stage of the cell division cycle, is a tightly controlled process amongst all eukaryotes, with defective division leading to severe cellular consequences and implicated in serious human diseases and conditions such as cancer ...
Imane M. Rezig, Wandiahyel G. Yaduma, Christopher J. McInerny   +2 more
doaj   +1 more source

Predicting growth and finding biomass production using the general growth mechanism [PDF]

Yu. K. Shestopaloff, Biophysical Reviews and Letters, 2012, Vol. 7, No. 3-4, p. 177-195, 2013
First, we briefly describe the general growth mechanism, which governs the growth of living organisms, and its mathematical representation, the growth equation. Using the growth equation, we compute growth curve for S. cerevisiae and show that it corresponds to available experimental data. Then, we propose a new method for finding amount of synthesized
arxiv   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

The FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika, Antonia Paić, Ana Novačić, Tea Martinić Cezar, Béatrice Vallée, Renata Teparić, Igor Stuparević, Bojan Žunar   +7 more
wiley   +1 more source

FRET Microscopy in Yeast

Biosensors, 2019
Förster resonance energy transfer (FRET) microscopy is a powerful fluorescence microscopy method to study the nanoscale organization of multiprotein assemblies in vivo.
Michal Skruzny, Emma Pohl, Marc Abella
doaj   +1 more source

Force and length-dependent catastrophe activities explain interphase microtubule organization in fission yeast [PDF]

, 2008
The cytoskeleton is essential for the maintenance of cell morphology in eukaryotes. In fission yeast for example, polarized growth sites are organized by actin whereas microtubules (MT) acting upstream control where growth occurs (La Carbona et al, 2006).
arxiv   +1 more source

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander, Mehats, Alizée, Osman, Fekret, Whitby, Matthew C   +3 more
core   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

The FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher, Yun Jin Pai, Alex Pines, Wim Vermeulen   +3 more
wiley   +1 more source

Metabolic studies on Schizosaccharomyces pombe for improved protein secretion [PDF]

, 2013
Die Spalthefe Schizosaccharomyces pombe stellt ein attraktives System zur heterologen Proteinsekretion dar, kann derzeit aber noch nicht mit Zellfabriken wie Pichia pastoris und Saccharomyces cerevisiae konkurrieren. Diese Arbeit sollte daher das Verständnis des Metabolismus von S. pombe und dessen Belastung durch Sekretion von Proteinen vergrößern, um
openaire   +1 more source

Characterization of Sro1, a novel stress responsive protein in Schizosaccharomyces pombe [PDF]

FEMS Yeast Research, 2008
The large amount of available genome sequencing data presents a huge challenge in the form of orphan sequences. This study reports the detailed functional characterization of one such orphan sequence in Schizosaccharomyces pombe. We identified this gene as a prominently upregulated 1.4 kb transcript in a screen for Cigarette smoke extract responsive ...
Sheelarani Karunanithi, Dhrubajyoti Chattopadhyay, Sibapriya Chaudhuri, Geetanjali Sundaram, Santanu Palchaudhuri   +4 more
openaire   +3 more sources