Neural Regeneration ResearchSchwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties. A the Food and Drug Administration-approved Phase I clinical trial has
Wenrui Qu +15 more
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Adhesion of axolemmal fragments to Schwann cells: a signal- and target- specific process closely linked to axolemmal induction of Schwann cell mitosis [PDF]
, 1985 Gen Sobue, David Pleasure
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Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
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Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures. [PDF]
, 1989 S Jaakkola +4 more
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A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
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Octopaminergic Modulation of the Membrane Potential of the Schwann Cell of the Squid Giant Nerve Fibre [PDF]
, 1986 Vincenzina Reale +2 more
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The Journal of Pathology, EarlyView.Abstract High‐risk neuroblastomas exhibit a high degree of intratumoral heterogeneity. Single‐cell RNA sequencing has greatly improved our understanding of these tumors, but the method lacks cellular tissue context and spatial information about local signaling dynamics.
Joachim T Siaw +10 more
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Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation
Sensory Neuroscience, EarlyView.ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera +3 more
wiley +1 more source
Conductive Materials and Electrical Stimulation for Auditory Restoration
Sensory Neuroscience, EarlyView.Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao +8 more
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Pulsatile and myelin‐forming activities of Schwann cells in vitro
, 1966 Susi Ernyei, M. R. Young
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