Results 131 to 140 of about 49,600 (309)
Brain Pathology, EarlyView.Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li +7 more
wiley +1 more source
Anti‐nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation
British Journal of Pharmacology, EarlyView.Background and Purpose Leonurine, a pseudoalkaloid derived from Leonotis leonurus, has been traditionally used in herbal medicine to alleviate conditions such as headaches and abdominal discomfort. Its therapeutic effects are often attributed to potential antioxidant properties; however, the precise molecular mechanisms remain poorly understood ...
Matilde Marini +20 more
wiley +1 more source
The functional characteristics of Schwann cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve [PDF]
, 1994 AD Levi +3 more
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British Journal of Pharmacology, EarlyView.Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
Axons regulate Schwann cell expression of the POU transcription factor SCIP [PDF]
, 1994 SS Scherer +5 more
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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1960 openaire +2 more sources
Cancer Science, EarlyView.Mesenchymal fibroblasts were significantly expanded in desmoid fibromatosis (DF), and the mesenchymal fibroblasts in DF were further divided into two subtypes according to the differentiation states. ADAM12 and CREB3L1 were identified as the specific marker and transcription factor for DF.
Junfeng Wang +7 more
wiley +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
Cell Proliferation, EarlyView.The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
Ion channels in axon and Schwann cell membranes at paranodes of mammalian myelinated fibers studied with patch clamp [PDF]
, 1990 G F Wilson, SY Chiu
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