Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV
We developed a prediction model of biological age based on 77 plasma proteins that were associated with chronological age in two independent cohorts of PLHIV and one cohort of people without HIV. PLHIV exhibited an increased age advancement that was positively associated with previous co‐infections and non‐AIDS‐related comorbidities, a higher ...
Adriana Navas+10 more
wiley +1 more source
The neurones are the cells of the nervous system and are surrounded and protected by glials cells. In the peripheral nervous system the Schwann cells (SC) are the glia of the nerves.
Sandra Perdomo, Clara Spinel
doaj
Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang+22 more
wiley +1 more source
Controlling tissue size by active fracture [PDF]
Groups of cells, including clusters of cancerous cells, multicellular organisms, and developing organs, may both grow and break apart. What physical factors control these fractures? In these processes, what sets the eventual size of clusters? We develop a framework for understanding cell clusters that can fragment due to cell motility using an active ...
arxiv
Schwann Cells in Neuromuscular Disorders: A Spotlight on Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disease primarily affecting motor neurons, leading to progressive muscle atrophy and paralysis.
Kathryn R. Moss, Smita Saxena
doaj +1 more source
Pulsatile and myelin‐forming activities of Schwann cells in vitro
Susi Ernyei, M. R. Young
openalex +1 more source
Isolation and functional characterization of Schwann cells derived from adult peripheral nerve [PDF]
TK Morrissey, Naomi Kleitman, RP Bunge
openalex +1 more source
CAPRIN1 Pro512Leu Variant Causes Childhood Dementia, Myoclonus‐Ataxia, and Sensorimotor Neuropathy
Movement Disorders Clinical Practice, EarlyView.
Rossella Bove+11 more
wiley +1 more source
Effects of tubocurarine and eserine on the axon‐Schwann cell relationship in the squid nerve fibre
Jorge Villegas
openalex +2 more sources
Mitogen-expanded Schwann cells retain the capacity to myelinate regenerating axons after transplantation into rat sciatic nerve. [PDF]
M. Laura Feltri+4 more
openalex +1 more source