Inhibition of ErbB2 mitigates secondary denervation after traumatic muscle injury
Abstract figure legend Our study evaluated the therapeutic potential of ErbB2 inhibition (Herceptin) after volumetric muscle loss (VML) injury, primarily evaluating improvements at the neuromuscular junctions (NMJ). A full thickness model of VML injury to the tibialis anterior muscle of adult Lewis rats was used, and treatments included Herceptin, a ...
Jacob R. Sorensen+6 more
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A dose escalation and safety study of AAVrh10-mediated Schwann cell-targeted gene therapy for CMT1X. [PDF]
Christou M+7 more
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Polarization of myelinating Schwann cell surface membranes: role of microtubules and the trans-Golgi network [PDF]
BD Trapp+5 more
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Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice
Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi+9 more
wiley +1 more source
Extra-pineal melatonin in perisynaptic Schwann cell-muscle fiber cross talk at the regenerating neuromuscular junction. [PDF]
Negro S, Montecucco C, Rigoni M.
europepmc +1 more source
Impaired peripheral nerve regeneration in a mutant strain of mice (Enr) with a Schwann cell defect [PDF]
EM Rath+3 more
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Main Points OECs, SCs, and Mel derive from SCPs. Sox10Cre;YapHet;TazKO mice show impaired SC maturation, reduced Mel formation, fewer SCPs, OECs, and olfactory neurons, but normal GnRH‐1 neuron migration. ABSTRACT Olfactory Ensheathing Cells (OECs) are glial cells originating from the neural crest and are critical for bundling olfactory axons to the ...
Ed Zandro M. Taroc+7 more
wiley +1 more source
Potential Role of CD99 Signaling Pathway in Schwann Cell Dysfunction in Diabetic Foot Ulcers Based on Single-Cell Transcriptome Analysis. [PDF]
Zhou Y, Zhou Y, Chen H, Zhang L, Bi S.
europepmc +1 more source
Multiple kinetic components of sodium channel inactivation in rabbit Schwann cells.
James R. Howe, J. M. Ritchie
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