Results 31 to 40 of about 128,417 (336)
Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 5001-5012, December 2022., 2022 Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki +9 more
wiley +1 more source
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]
, 2012 The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Arthur-Farraj, PJ +16 more
core +1 more source
Cell morphologies in the nervous system: Glia steal the limelight
Journal of Comparative Neurology, Volume 531, Issue 3, Page 338-343, February 2023., 2023 Diversity of digitally reconstructed glia (astrocytes, oligodendrocytes, microglia, and other types) freely available for download and reuse at NeuroMorpho.Org in terms of experimental provenance, animal species, anatomical region, cell type, tracing platform, and more.
Giorgio A. Ascoli
wiley +1 more source
Neural Regeneration Research, 2018 Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in clinical trials. In our continuing efforts to improve Schwann cell transplantation strategies, we sought to determine the combined ...
Yee-Shuan Lee +3 more
doaj +1 more source
Nerve growth factor signaling through p75 induces apoptosis in Schwann cells via a Bcl-2-independent pathway [PDF]
, 1999 Apoptosis is involved in the regulation of Schwann cell numbers during normal development and after axonal damage, but the molecular regulation of Schwann cell death remains unknown.
Bartlett, Perry F. +5 more
core +2 more sources
Biochemistry and Biophysics Reports, 2023 Bell's palsy is the most common form of facial nerve palsy. This study aimed to explore the pathogenesis of Bell's palsy by investigating the effect of cold-stimulated adipocyte supernatant on adhesion molecule expression in Schwann cell line.
Tiefeng Zhang +6 more
doaj
Edaravone combined with Schwann cell transplantation may repair spinal cord injury in rats
Neural Regeneration Research, 2015 Edaravone has been shown to delay neuronal apoptosis, thereby improving nerve function and the microenvironment after spinal cord injury. Edaravone can provide a favorable environment for the treatment of spinal cord injury using Schwann cell ...
Shu-quan Zhang +6 more
doaj +1 more source
A Study of Qualitative Correlations Between Crucial Bio-markers and the Optimal Drug Regimen of Type-I Lepra Reaction: A Deterministic Approach [PDF]
arXiv, 2023 Mycobacterium leprae is a bacteria that causes the disease Leprosy (Hansen's disease), which is a neglected tropical disease. More than 200000 cases are being reported per year world wide. This disease leads to a chronic stage known as Lepra reaction that majorly causes nerve damage of peripheral nervous system leading to loss of organs.
arxiv
The repair Schwann cell and its function in regenerating nerves. [PDF]
, 2016 Nerve injury triggers the conversion of myelin and non-myelin (Remak) Schwann cells to a cell phenotype specialised to promote repair. Distal to damage, these repair Schwann cells provide the necessary signals and spatial cues for the survival of injured
Jessen, KR, Mirsky, R
core +1 more source
Cell Transplantation, 2013 Olfactory mucosa (OM)-derived olfactory ensheathing cells (OECs) are attractive candidates for autologous cell transplantation-based therapy of nervous system injury.
Susanne Ziege +2 more
doaj +1 more source