Results 21 to 30 of about 5,296,721 (231)
Mining Gene Ontology Data with AGENDA
Bioinformatics and Biology Insights, 2012 The Gene Ontology (GO) initiative is a collaborative effort that uses controlled vocabularies for annotating genetic information. We here present AGENDA ( A pplication for mining Gen e Ontology Da ta), a novel web-based tool for accessing the GO database.
Guvanch Ovezmyradov +2 more
doaj +1 more source
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]
, 2002 Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
George K. Tofaris +7 more
core +1 more source
High conductance anion channel in Schwann cell vesicles from rat spinal roots [PDF]
, 1992 Potassium uptake, possibly together with chloride, is one of the presumed functions of Schwann cells in the peripheral nervous system. However, the presence of chloride channels has not been demonstrated in adult Schwann cells.
Quasthoff, Stefan +5 more
core +1 more source
Functional role of the overexpression of the myelin and lymphocyte protein MAL in Schwann cells [PDF]
, 2013 For fast propagation of action potentials in the nervous system, higher vertebrates have developed a specialized plasma membrane structure, the myelin, ensheathing nerve fibers. Myelin sheaths are formed by Schwann cells in the peripheral nervous system (
Schmid, Daniela
core +1 more source
Rab27a/Slp2-a complex is involved in Schwann cell myelination
Neural Regeneration Research, 2016 Myelination of Schwann cells in the peripheral nervous system is an intricate process involving myelin protein trafficking. Recently, the role and mechanism of the endosomal/lysosomal system in myelin formation were emphasized.
Wen-feng Su +7 more
doaj +1 more source
Transcriptional Regulation Induced by cAMP Elevation in Mouse Schwann Cells
ASN Neuro, 2014 In peripheral nerves, Schwann cell development is regulated by a variety of signals. Some of the aspects of Schwann cell differentiation can be reproduced in vitro in response to forskolin, an adenylyl cyclase activator elevating intracellular cAMP ...
Daniela Schmid +2 more
doaj +1 more source
Neural Regeneration Research, 2018 Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in clinical trials. In our continuing efforts to improve Schwann cell transplantation strategies, we sought to determine the combined ...
Yee-Shuan Lee +3 more
doaj +1 more source
Edaravone combined with Schwann cell transplantation may repair spinal cord injury in rats
Neural Regeneration Research, 2015 Edaravone has been shown to delay neuronal apoptosis, thereby improving nerve function and the microenvironment after spinal cord injury. Edaravone can provide a favorable environment for the treatment of spinal cord injury using Schwann cell ...
Shu-quan Zhang +6 more
doaj +1 more source
Cell Transplantation, 2013 Olfactory mucosa (OM)-derived olfactory ensheathing cells (OECs) are attractive candidates for autologous cell transplantation-based therapy of nervous system injury.
Susanne Ziege +2 more
doaj +1 more source
Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]
, 2012 Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan +4 more
core +1 more source