Results 11 to 20 of about 59,053 (258)
Inhibition of Schwann Cell Pyroptosis Promotes Nerve Regeneration in Peripheral Nerve Injury in Rats
Mediators of Inflammation, 2023 Background. Peripheral nerve injury (PNI) is one of the most debilitating injuries, but therapies for PNI are still far from satisfactory. Pyroptosis, a recently identified form of cell death, has been demonstrated to participate in different diseases ...
Jiayi Wang +9 more
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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
Cell Reports, 2023 Summary: Schwann cells play critical roles in peripheral neuropathies; however, the regulatory mechanisms of their homeostasis remain largely unknown. Here, we show that nucleoporin Seh1, a component of nuclear pore complex, is important for Schwann cell
Mei Wu +19 more
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Advanced ScienceNeural structures are widely distributed in the oral and maxillofacial region and play important roles in the progression of head and neck squamous cell carcinoma (HNSCC).
Xiaoyan Meng +7 more
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Research progress on mechanism of Schwann cells promoting peripheral nerve regeneration [PDF]
Jichu yixue yu linchuang, 2022 Schwann cells (SCs) have a strong plasticity. After peripheral nerve injury, Schwann cells dedifferentiate into repair phenotype and dominate the repair process. C-Jun N-terminal kinase, mitogen activated protein kinase(MAPK) and other signaling pathways
YANG Yi-duo, GUO Hai-dong, SHAO Shui-jin, LIU Yu-pu
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Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. [PDF]
PLoS ONE, 2010 The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discrete steps.
Juliane Bremer +5 more
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Embryonic Schwann cell development: the biology of Schwann cell precursors and early Schwann cells
Journal of Anatomy, 1997 The cellular events leading to the generation of Schwann cells from the neural crest have recently been clarified and it is now possible to outline a relatively simple model of the Schwann cell lineage in the rat and mouse. Neural crest cells have to undergo 3 main developmental transitions to become mature Schwann cells.
K R, Jessen, R, Mirsky
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PLoS ONE, 2020 Transference of RNAs and ribosomes from Schwann cell-to-axon was demonstrated in normal and regenerating peripheral nerves. Previously, we have shown that RNAs transfer is dependent on F-actin cytoskeleton and Myosin Va.
Lucía Canclini +6 more
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Molecular Medicine, 2021 Background Growth factors execute essential biological functions and affect various physiological and pathological processes, including peripheral nerve repair and regeneration.
Yaxian Wang +7 more
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PLoS ONE, 2021 IntroductionPolyneuropathy is a debilitating condition characterized by distal sensory and motor deficits. Schwann cell dysfunction and axonal loss are integral factors in pathophysiology and disease progression of polyneuropathy.AimsThe aim of this ...
Eva Placheta-Györi +4 more
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Integrative study of Arabidopsis thaliana metabolomic and transcriptomic data with the interactive MarVis-Graph software [PDF]
PeerJ, 2014 State of the art high-throughput technologies allow comprehensive experimental studies of organism metabolism and induce the need for a convenient presentation of large heterogeneous datasets.
Manuel Landesfeind +6 more
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