Results 11 to 20 of about 64,431 (291)
The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy [PDF]
Frontiers in Cellular Neuroscience, 2022 Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang +8 more
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Schwann cells in regeneration and cancer
Frontiers in PharmacologySchwann cells are specific peripheral glial cells with remarkable plasticity following peripheral nerve injury. Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and ...
Lan Zhang +4 more
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Rab27a/Slp2-a complex is involved in Schwann cell myelination
Neural Regeneration Research, 2016 Myelination of Schwann cells in the peripheral nervous system is an intricate process involving myelin protein trafficking. Recently, the role and mechanism of the endosomal/lysosomal system in myelin formation were emphasized.
Wen-feng Su +7 more
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Stem Cell Reports, 2017 Schwann cells play a crucial role in successful nerve repair and regeneration by supporting both axonal growth and myelination. However, the sources of human Schwann cells are limited both for studies of Schwann cell development and biology and for the ...
Han-Seop Kim +7 more
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Acta Biológica Colombiana, 2004 The neurones are the cells of the nervous system and are surrounded and protected by glials cells. In the peripheral nervous system the Schwann cells (SC) are the glia of the nerves.
Sandra Perdomo, Clara Spinel
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Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential. [PDF]
PLoS ONE, 2011 Multipotent somatic stem cells have been identified in various adult tissues. However, the stem/progenitor cells of the peripheral nerves have been isolated only from fetal tissues.
Takehiko Takagi +10 more
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Frontiers in Cellular Neuroscience, 2021 Embryonic Dissociated Dorsal Root Ganglia (DRG) cultures are often used to investigate the role of novel molecular pathways or drugs in Schwann cell development and myelination.
Venkat Krishnan Sundaram +7 more
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The immunocompetence of Schwann cells [PDF]
Muscle & Nerve, 2007 AbstractSchwann cells are the myelinating glial cells of the peripheral nervous system that support and ensheath axons with myelin to enable rapid saltatory signal propagation in the axon. Immunocompetence, however, has only recently been recognized as an important feature of Schwann cells.
Gerd, Meyer zu Hörste +4 more
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Biochemistry and Biophysics Reports, 2023 Bell's palsy is the most common form of facial nerve palsy. This study aimed to explore the pathogenesis of Bell's palsy by investigating the effect of cold-stimulated adipocyte supernatant on adhesion molecule expression in Schwann cell line.
Tiefeng Zhang +6 more
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Inhibition of Schwann Cell Pyroptosis Promotes Nerve Regeneration in Peripheral Nerve Injury in Rats
Mediators of Inflammation, 2023 Background. Peripheral nerve injury (PNI) is one of the most debilitating injuries, but therapies for PNI are still far from satisfactory. Pyroptosis, a recently identified form of cell death, has been demonstrated to participate in different diseases ...
Jiayi Wang +9 more
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