Results 31 to 40 of about 64,633 (286)

Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush [PDF]

, 2007
Multiple molecular mechanisms influence nerve regeneration. Because serine proteases were shown to affect peripheral nerve regeneration, we performed nerve crush experiments to study synapse reinnervation in adult mice lacking the serpin protease nexin-1
Atanasoski, Suzana, Suter, Ueli, Kvajo, Mirna, Fayard, Bérengère, Moreno, Eliza, Lino, Maria Maddalena, Brenner, Hans Rudolf, Monard, Denis   +7 more
core   +1 more source

Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]

, 2012
Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan, Kaltschmidt, Christian, Widera, Darius, Widera, Darius ; https://orcid.org/, Kaltschmidt, Barbara   +4 more
core   +2 more sources

Macrophages Regulate Schwann Cell Maturation after Nerve Injury

Cell Reports, 2018
Summary: Pro-regenerative macrophages are well known for their role in promoting tissue repair; however, their specific roles in promoting regeneration of the injured nerve are not well defined.
Jo Anne Stratton, Alexandra Holmes, Nicole L. Rosin, Sarthak Sinha, Mohit Vohra, Nicole E. Burma, Tuan Trang, Rajiv Midha, Jeff Biernaskie   +8 more
doaj   +1 more source

Macrophage depletion and Schwann cell transplantation reduce cyst size after rat contusive spinal cord injury

Neural Regeneration Research, 2018
Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in clinical trials. In our continuing efforts to improve Schwann cell transplantation strategies, we sought to determine the combined ...
Yee-Shuan Lee, Lucy H Funk, Jae K Lee, Mary Bartlett Bunge   +3 more
doaj   +1 more source

Edaravone combined with Schwann cell transplantation may repair spinal cord injury in rats

Neural Regeneration Research, 2015
Edaravone has been shown to delay neuronal apoptosis, thereby improving nerve function and the microenvironment after spinal cord injury. Edaravone can provide a favorable environment for the treatment of spinal cord injury using Schwann cell ...
Shu-quan Zhang, Min-fei Wu, Zhe Piao, Jin Yao, Ji-hai Li, Xin-gang Wang, Jun Liu   +6 more
doaj   +1 more source

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M., Susan C Barnett, Gunn-Moore Frank J., Tilston-Lunel, Andrew Martin, Moleirinho, S., Jennifer R Higginson, Angus Liselotte, Prystowsky Michael B., Calum Patrick, Liselotte Angus, Andrew M. Tilston-lünel, Michael B. Prystowsky, Patrick, C., Susana Moleirinho, Frank J Gunn-Moore, Moleirinho Susana, Gunn-Moore, Frank J, Gunn-Moore, F.J., Prystowsky, M.B., Moleirinho, Susan, Paul A. Reynolds, Maciej Antkowiak, Susan C. Barnett, Jennifer R. Higginson, Antkowiak Maciej, Barnett Susan C., Paul A Reynolds, Higginson, J.R., Reynolds Paul A., Antkowiak, Maciej, Prystowsky, Michael, Michael B Prystowsky, Barnett, Susan, Antkowiak, M., Reynolds, Paul Andrew, Tilston-Lünel Andrew M., Barnett, S.C., Frank J. Gunn-moore, Angus, Liselotte, Andrew M Tilston-Lünel, Patrick Calum, Patrick, Calum, Higginson Jennifer R., Higginson, JR, Angus, L., Reynolds, P.A.   +45 more
core   +1 more source

Toward Defining the Regenerative Potential of Olfactory Mucosa: Establishment of Schwann Cell-Free Adult Canine Olfactory Ensheathing Cell Preparations Suitable for Transplantation

Cell Transplantation, 2013
Olfactory mucosa (OM)-derived olfactory ensheathing cells (OECs) are attractive candidates for autologous cell transplantation-based therapy of nervous system injury.
Susanne Ziege, Wolfgang Baumgärtner, Konstantin Wewetzer   +2 more
doaj   +1 more source

The Protooncogene Ski Controls Schwann Cell Proliferation and Myelination [PDF]

, 2004
Schwann cell proliferation and subsequent differentiation to nonmyelinating and myelinating cells are closely linked processes. Elucidating the molecular mechanisms that control these events is key to the understanding of nerve development, regeneration,
Lee, Hye-Youn, Young, Peter, Ehrengruber, MU, Notterpek, Lucia, Young, P, Ehrengruber, Markus U., Atanasoski, Suzana, Colmenares, C, Sommer, Lukas, Stavnezer, Ed, Castagner, F, Castagner, François, Sommer, L, Suter, U, Ehrengruber, Markus U, Stavnezer, E, Suter, Ueli, Lee, H-Y, Meijer, Dies, Colmenares, Clemencia, Atanasoski, S, Notterpek, L   +21 more
core   +1 more source

Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair

Cell Reports, 2019
Summary: Regenerative paradigms exhibit nerve dependency, including regeneration of the mouse digit tip and salamander limb. Denervation impairs regeneration and produces morphological aberrancy in these contexts, but the direct effect of innervation on ...
R. Ellen Jones, Ankit Salhotra, Kiana S. Robertson, Ryan C. Ransom, Deshka S. Foster, Harsh N. Shah, Natalina Quarto, Derrick C. Wan, Michael T. Longaker   +8 more
doaj   +1 more source

The septin cytoskeleton is associated with distinct myelin structures of the central and peripheral nervous system [PDF]

, 2008
Rapid conduction of nerve impulses in the nervous system of higher vertebrates is made possible by ensheathment of nerve fibers by the specialized plasma membrane structure myelin. Consequently, failure of myelination or damage to the myelin sheath leads
Buser, Andres
core   +1 more source