Results 71 to 80 of about 5,296,721 (231)

TRPV4 activation in Schwann cells mediates mechanically induced pain of oral cancer

Frontiers in Pain Research
IntroductionPatients with oral cancer often experience intense functional pain due to mechanical stimulation at the cancer site. The role of mechanosensitive ion channels in oral cancer pain, such as TRPV4, is not fully understood.ObjectivesOur objective
Yatendra Mulpuri, Yatendra Mulpuri, Nguyen H. Tu, Nguyen H. Tu, Kenji Inoue, Kenji Inoue, Grace Harden, Grace Harden, Samuel J. Nicholson, Samuel J. Nicholson, Anisa Seenauth, Anisa Seenauth, Yan Huang, Yan Huang, Keylin G. Escobar, Keylin G. Escobar, Yalda Moayedi, Yalda Moayedi, Nigel W. Bunnett, Nigel W. Bunnett, Nigel W. Bunnett, Nigel W. Bunnett, Donna G. Albertson, Donna G. Albertson, Brian L. Schmidt, Brian L. Schmidt, Brian L. Schmidt   +26 more
doaj   +1 more source

Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression

Frontiers in Cellular Neuroscience, 2019
Schwann cell reprogramming and differentiation are crucial prerequisites for neuronal regeneration and re-myelination to occur following injury to peripheral nerves. The neurotrophin receptor p75NTR has been identified as a positive modulator for Schwann
Nádia P. Gonçalves, Nádia P. Gonçalves, Simin Mohseni, Marwa El Soury, Maj Ulrichsen, Mette Richner, Junhua Xiao, Rhiannon J. Wood, Olav M. Andersen, Elizabeth J. Coulson, Stefania Raimondo, Simon S. Murray, Christian B. Vægter, Christian B. Vægter   +13 more
doaj   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

Reprogramming diminishes retention of Mycobacterium leprae in Schwann cells and elevates bacterial transfer property to fibroblasts [v3; ref status: indexed, http://f1000r.es/2ae]

F1000Research, 2013
Background: Bacterial pathogens can manipulate or subvert host tissue cells to their advantage at different stages during infection, from initial colonization in primary host niches to dissemination. Recently, we have shown that Mycobacterium leprae (ML),
Toshihiro Masaki, Aidan McGlinchey, Simon R. Tomlinson, Jinrong Qu, Anura Rambukkana   +4 more
doaj   +1 more source

Letter by habib and schwann regarding article, bilateral internal mammary artery grafting enhances survival in diabetic patients: A 30-year follow-up of propensity score-matched cohorts

, 2013
[No abstract available]Dorman MJ, 2012, CIRCULATION, V126, P2935, DOI 10.1161-CIRCULATIONAHA.112.117606; Schwann TA, 2013, EUR J CARDIO-THORAC; Schwann TA, 2008, EUR J CARDIO-THORAC, V33, P914, DOI 10.1016-j.ejcts.2008.01.062; Zacharias A, 2004 ...
Schwann T.A., Habib R.H.
core   +1 more source

Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota, Erika S. Lisboa, Victoria L. S. dos Santos, Carine Serafim, Maria L. F. Bezerra, Thais F. R. Alves, Marco V. Chaud, Frederico S. Martins, Juliana C. Cardoso, Eliana B. Souto, Patrícia Severino   +10 more
wiley   +1 more source

mTORC1 is essential for early steps during Schwann cell differentiation of amniotic fluid stem cells and regulates lipogenic gene expression.

PLoS ONE, 2014
Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage.
Andrea Preitschopf, Kongzhao Li, David Schörghofer, Katharina Kinslechner, Birgit Schütz, Ha Thi Thanh Pham, Margit Rosner, Gabor Jozsef Joo, Clemens Röhrl, Thomas Weichhart, Herbert Stangl, Gert Lubec, Markus Hengstschläger, Mario Mikula   +13 more
doaj   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell–derived exosomal vesicles: a case report

Neural Regeneration Research
Schwann cells are essential for the maintenance and function of motor neurons, axonal networks, and the neuromuscular junction. In amyotrophic lateral sclerosis, where motor neuron function is progressively lost, Schwann cell function may also be ...
Pascal J. Goldschmidt-Clermont, Aisha Khan, George Jimsheleishvili, Patricia Graham, Adriana Brooks, Risset Silvera, Alexander J.P. Goldschmidt, Damien D. Pearse, W. Dalton Dietrich, Allan D. Levi, James D. Guest   +10 more
doaj   +1 more source

Therapeutic strategies for peripheral nerve injury: decellularized nerve conduits and Schwann cell transplantation

Neural Regeneration Research, 2019
In recent years, the use of Schwann cell transplantation to repair peripheral nerve injury has attracted much attention. Animal-based studies show that the transplantation of Schwann cells in combination with nerve scaffolds promotes the repair of ...
Gong-Hai Han, Jiang Peng, Ping Liu, Xiao Ding, Shuai Wei, Sheng Lu, Yu Wang   +6 more
doaj   +1 more source