Results 131 to 140 of about 106,917 (289)

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Neural-Competent Cells of Adult Human Dermis Belong to the Schwann Lineage [PDF]

, 2014
Usue Etxaniz, Adrián Pérez-San Vicente, Nuria Gago‐López, Mario García‐Domínguez, Haizea Iribar, Ariane Aduriz, Virginia Pérez‐López, Izaskun Burgoa, Haritz Irizar, Maider Muñoz‐Culla, Ainara Vallejo‐Illarramendi, Olatz Leis, Ander Matheu, Ángel G. Martín, David Otaegui, M P Lopez-Mato, Araika Gutiérrez‐Rivera, Robb MacLellan, Ander Izeta   +18 more
openalex   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source

Engineered Neural Tissue (EngNT) Containing Human iPSC-Derived Schwann Cell Precursors Promotes Axon Growth in a Rat Model of Peripheral Nerve Injury

Bioengineering
Tissue engineering has the potential to overcome the limitations of using autografts in nerve gap repair, using cellular biomaterials to bridge the gap and support neuronal regeneration.
Rebecca A. Powell, Emily A. Atkinson, Poppy O. Smith, Rickie Patani, Parmjit S. Jat, Owein Guillemot-Legris, James B. Phillips   +6 more
doaj   +1 more source

Nanoparticle‐integrated electrostimulation‐responsive biomaterials: Innovations in drug delivery and tissue repair in clinical regenerative medicine

Interdisciplinary Medicine, EarlyView.
Schematic representation of nanoparticle‐integrated electrostimulation‐responsive biomaterials for controlled drug delivery and tissue regeneration. Electroactive scaffolds including conductive polymers, electroresponsive hydrogels, and piezoelectric matrices are shown incorporating therapeutic nanoparticles (such as iron oxide, silver, and carbon ...
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Placental‐Derived Connective Tissue Matrix Mediates Murine Recurrent Laryngeal Nerve Regeneration

The Laryngoscope, EarlyView.
Placentally derived connective tissue matrix (pd‐CTM) innately contains various neurotrophic, angiogenic, anti‐inflammatory, and tissue remodeling cytokines. In this mouse model of unilateral vocal fold paralysis, we investigate its effects on recurrent laryngeal nerve (RLN) regeneration and reinnervation of the right thyroarytenoid (TA) muscle after ...
Sunjay Anekal, Ananya Tadikonda, Gabriel Sobczak, Lena W. Chen, Aditya Bhatt, Troy Wesson, Patrick R. Finnegan, Stacey Halum   +7 more
wiley   +1 more source

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

Movement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger, Chi Wang Ip   +1 more
wiley   +1 more source

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Movement Disorders, EarlyView.
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

Frailty, Surgical Time, and Surgical Complications Increase Length of Stay Following Large Vestibular Schwannoma Resection

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Patients with large vestibular schwannomas (VS) are at higher risk for adverse outcomes following microsurgical resection. This study aims to identify clinical and radiographic factors that may be predictive of adverse outcomes. Study Design Retrospective chart review. Setting Academic tertiary care center.
Jason L. Steele, Nicole J. Ewer, Heather J. Smith, Samira Takkoush, Melissa Shuhui Lee, Richard H. Wiggins, Mana Espahbodi, Neil S. Patel, Richard K. Gurgel   +8 more
wiley   +1 more source