Results 131 to 140 of about 51,731 (281)
Anti‐nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation
Background and Purpose Leonurine, a pseudoalkaloid derived from Leonotis leonurus, has been traditionally used in herbal medicine to alleviate conditions such as headaches and abdominal discomfort. Its therapeutic effects are often attributed to potential antioxidant properties; however, the precise molecular mechanisms remain poorly understood ...
Matilde Marini+20 more
wiley +1 more source
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro+14 more
wiley +1 more source
The functional characteristics of Schwann cells cultured from human peripheral nerve after transplantation into a gap within the rat sciatic nerve [PDF]
AD Levi+3 more
openalex +1 more source
Mesenchymal fibroblasts were significantly expanded in desmoid fibromatosis (DF), and the mesenchymal fibroblasts in DF were further divided into two subtypes according to the differentiation states. ADAM12 and CREB3L1 were identified as the specific marker and transcription factor for DF.
Junfeng Wang+7 more
wiley +1 more source
Axons regulate Schwann cell expression of the POU transcription factor SCIP [PDF]
SS Scherer+5 more
openalex +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
openaire +2 more sources
MFG‐E8 promotes oxidative stress by upregulating NOX4 and activating the MAPK pathway, which increases ROS production and affects vascular smooth muscle cell (VSMC) apoptosis, thereby driving the progression of abdominal aortic aneurysm (AAA). Resveratrol can inhibit the expression and function of MFG‐E8, reduce ROS generation, and lower the incidence ...
Jie Xiao+6 more
wiley +1 more source
Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception. [PDF]
Chen YT+12 more
europepmc +2 more sources