Results 141 to 150 of about 68,795 (281)

Efeito do FGF2 na diferenciação de células da crista neural truncal (CNT) de codornas in vitro [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Biológicas. Programa de Pós-Graduação em Neurociências.As células da crista neural (CN) têm origem a partir das bordas entre a placa neural e a epiderme durante o ...
Bittencourt, Denise Avani
core  

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone   +5 more
wiley   +1 more source

Selective expansion and long‐term culture of human schwann cells from sural nerve biopsies

open access: yes, 1995
Fragments of sural nerve biopsy specimens were cultured in the presence of the supernatant of lymphokine‐activated killer cells, resulting in the selective outgrowth of cells with bipolar or tripolar morphology, reminiscent of that of Schwann cells ...
Wokke, John J.H.   +5 more
core  

Bers-ERK Schwann Cells Coordinate Nerve Regeneration

open access: yes, 2012
In this issue of Neuron, Napoli et al. (2012) demonstrate that elevated ERK/MAPK signaling in Schwann cells is a crucial trigger for Schwann cell dedifferentiation in vivo. Moreover, the authors show that dedifferentiated Schwann cells have the potential
Snider, William D., Newbern, Jason M.
core   +1 more source

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

open access: yesJournal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian   +3 more
wiley   +1 more source

Proliferative Effects of Chishao on Schwann Cells are FGF-uPA, and ERK- and JNK-Dependent

open access: yes, 2012
[[abstract]]"This study evaluated the proliferative effects of chishao on RSC96, Schwann cells. A dose-dependent proliferative effect of chishao was obtained by methylthiazol tetrazolium (MTT), proliferating cell nuclear antigen (PCNA) Western blotting ...
Huang, Kun Shan;Lu, Min-Jin;Chen, Yueh-Sheng;Tsai, Fuu-Jen;Kuo, Wei-Wen;Cheng, Yi-Chang;Lin, Chien-Chung;Tsai, Chang-Hai;黃志揚;HUANG, CHIH-YANG;Lin, Jaung-Geng;Ou, Hsiu-Chung
core  

Schwann cells demonstrated lineage plasticity in culture and acquired oligodendrocyte phenotypes

open access: yes, 2017
Schwann cells and oligodendrocytes are myelin-forming glial cells found in the peripheral and central nervous systems, respectively. Despite being similar in function, the two cell types have distinct developmental origins.
Wu, KLK, Tsui, YP, Shum, DKY, Chan, YS
core  

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor   +9 more
wiley   +1 more source

The role of the extracellular matrix in Schwann cell development and myelination

open access: yes, 2007
INTRODUCTION The cellular components of the peripheral nervous system (PNS) - neurons and their axons, Schwann cells, perineurial cells, endoneurial fibroblasts and vessel endothelia - are surrounded by extracellular components such as collagens ...
Feltri M, Wrabetz L.
core  

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

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