Results 141 to 150 of about 62,084 (247)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira   +6 more
wiley   +1 more source

A Rapid Method to Immortalize Schwann Cells. [PDF]

open access: yesPediatr Discov
Zhang Y   +5 more
europepmc   +1 more source

Peripheral regeneration of Aβ low‐threshold mechanoreceptors is limited despite activation of regenerative transcriptional pathways

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar   +3 more
wiley   +1 more source

Preoperative Diagnosis of the Bile Duct Traumatic Neuroma by Endoscopic Ultrasound‐guided Tissue Acquisition: A Case Report

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Traumatic neuroma of the cystic duct stump is a rare benign lesion that may mimic biliary malignancy, making preoperative diagnosis challenging. We report a case of an enhancing lesion at the cystic duct stump after cholecystectomy that was diagnosed by endoscopic ultrasound‐guided tissue acquisition (EUS‐TA).
Kiyohiro Saito   +8 more
wiley   +1 more source

Schwann Cell‐Specific ATG7‐Dependent Autophagy Protects Myelin in a Mouse Model of Krabbe Disease

open access: yesGlia, Volume 74, Issue 12, December 2026.
Krabbe disease (KD) is caused by mutations in GALC and deregulated lysosomal function in Schwann cells (SCs). Using a SC‐specific Galc‐cKO mouse, we identified altered autophagy in SCs during KD progression. Further ablation of Atg7 in SCs of KD worsened disease severity.
Narayan Dhimal   +8 more
wiley   +1 more source

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