Results 161 to 170 of about 61,604 (256)

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

Advanced Science, Volume 13, Issue 49, 3 September 2026.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang, Zhihan Zhou, Qipeng Xie, Zheng Wang, Lijiong He, Yutong Liu, Lijuan Huang, Liuxian Ye, Limeng Hu, Baokun Li, Yang Wang, Xiaohui Hua, Xuelei Liu, Yunping Zhao, Jingxia Li, Jinfei Chen, Guiying Wang, Xian Shen, Wei Chen, Chuanshu Huang   +19 more
wiley   +1 more source

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis. [PDF]

Glia
Trimarco A, Audano M, La Marca R, Pellegatta M, Canevazzi P, Cariello M, Falco M, Pedretti S, Imperato G, Cestaro A, Podini P, Dina G, Quattrini A, Massimino L, Caruso D, Mitro N, Taveggia C.   +16 more
europepmc   +1 more source

Enhanced integrin-mediated adhesion and proliferation of Schwann cells using highly aligned, dual-functional fibrous scaffolds. [PDF]

NPJ Soft Matter
Chan YM, Judge NG, Willits RK, Becker ML.   +3 more
europepmc   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, Volume 13, Issue 53, 24 September 2026.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

MAPK-dependent release of GDNF from Schwann cells mediates tumor-independent pain in neurofibromatosis 1. [PDF]

Sci Signal
Raut NGR, Sprague KL, Adlakha A, Rupert AR, Hofmann MC, Queme LF, Ratner N, Jankowski MP.   +7 more
europepmc   +1 more source

Piezo‐Coupling Effects in Smart Polymers: Toward Ultrasensitive Sensing and Biomedical Applications

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Piezo‐coupling effects are the foundational factors for the development of multifunctional and self‐powered platforms. Central to this advancement is the use of stimuli‐responsive smart polymers, which offer mechanical flexibility, biocompatibility, and simplified structural complexity with improved sensitivity and energy efficiency.
Duc Khanh Tran, Tuan Sang Tran, Thanh‐An Truong, Trung‐Hieu Vu, That Buu Ton, Dzung Viet Dao, Van Thanh Dau   +6 more
wiley   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, Volume 100, Issue 3, Page 458-476, September 2026.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Nociceptive Schwann Cells Enter the Sensory Spotlight. [PDF]

J Invest Dermatol
Reznik AS, Cao C, Bunimovich YL.
europepmc   +1 more source

Decalcified and Decellularized Bone Conduits for Peripheral Nerve Regeneration: A Comparative In Vivo Study Using Rat Femur and Chicken Ulna Conduits

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Purpose: Peripheral nerve injuries (PNIs) pose a major clinical challenge, especially when nerve gaps exceed 5 mm and spontaneous regeneration is inadequate. This study aimed to evaluate the regenerative potential of novel bone‐derived nerve guidance conduits (NGCs) fabricated from rat femoral diaphysis and chicken ulna as alternatives to ...
Zahra Sepehri, Ali Moradi, Nasser Mahdavi‐Shahri, Morteza Behnam Rassouli   +3 more
wiley   +1 more source

Spinal cord transverse section hinders Wallerian degeneration and neoangiogenesis after peripheral nerve transection: Involvement of Schwann cells' miR-134-5p. [PDF]

IBRO Neurosci Rep
Jiang L, Zhang F, Qi F, Xu G, Xiao S, Armato U, Chiarini A, Prà ID, De Santis D, Deng C, Wei Z.   +10 more
europepmc   +1 more source