Results 171 to 180 of about 62,084 (247)

Targeting Ninjurin‐1‐Mediated Microglial Pyroptosis Attenuates Neuroinflammation and Neuronal Injury Following Intracerebral Hemorrhage

Brain and Behavior, Volume 16, Issue 11, November 2026.
In response to intracerebral hemorrhage, NF‐κB signaling upregulates Nlrp3 and Ninjurin‐1 (Ninj1) in microglia. NLRP3 inflammasome activation triggers GSDMD pore formation, whereas Ninj1 oligomerizes to execute terminal plasma membrane rupture (PMR) and DAMP release (such as HMGB1).
Liqiang Peng, Aosheng Peng, Hui Zhu, Ting Sun, Pan Liu, Ting Qi   +5 more
wiley   +1 more source

Interleukin-1β-Induced Inflammatory Signaling and Myelin-Related Alterations in Oligodendroglia and Schwann Cells in Multiple Sclerosis: Modulatory Effects of Ibuprofen and Flurbiprofen. [PDF]

Curr Issues Mol Biol
Narasimhappagari J, Liu L, Griffin WST.
europepmc   +1 more source

Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Ganglioneuroma (GN) may be misdiagnosed as neurofibroma when core needle biopsy samples only contain Schwannian stroma without mature ganglion cells. Even giant cervicothoracic GNs may be resectable through a transcervical approach alone.
Omar Daas, Somaya Al Kiswani, Mohammad Z. Al‐Qaisi, Ahmad Daas, Ashjan Al Shakkah, Sohaib Salahat, Abdullah Nofal   +6 more
wiley   +1 more source

Association of tumor Schwann cells with epithelial-mesenchymal transition and immune-suppressive microenvironment in triple-negative breast cancer. [PDF]

Breast Cancer Res Treat
Kawashima K, Elsaedy EA, Oshi M, Yamada A, Narui K, Gandhi S, Repasky E, Ishikawa T, Endo I, Takabe K.   +9 more
europepmc   +1 more source

Alpinia oxyphylla Miq.: Chemical Constituents, Neuroprotective and Metabolic Effects, and Translational Challenges—A Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Alpinia oxyphylla Miq. (AOM), a medicinal and edible resource, contains diphenylheptanoids, polysaccharides, flavonoids, terpenoids, and phenolic acids. These constituents exert multi‐target synergistic effects by modulating neuroinflammation, oxidative stress, and the PI3K/Akt pathway, thereby improving Alzheimer's disease, Parkinson's disease, and ...
Ziyan Yang, Hemei Yuan, Dengyou Nie, Jun Sheng, Titi Liu, Huanhuan Xu   +5 more
wiley   +1 more source

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis. [PDF]

Adv Sci (Weinh)
Wang Y, Xu L, Pan C, Cao R, Zeng P, Lyu X, Hu Q, Yan Z, Huang S, Dang N.   +9 more
europepmc   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

TRPV1 Agonist Capsaicin Enhances Oxidative-Stress Resistance and Regeneration in Dorsal Root Ganglia and Schwann Cells. [PDF]

Cells
Sarpong BK, Rilke N, Joswig L, Specht F, Tabar MS, Blusch A, Meichsner A, Renk P, Pedreiturria X, Grüter T, Klimas R, Winklhofer KF, Gold R, Sgodzai M, Pitarokoili K.   +14 more
europepmc   +1 more source

Claudin‐12‐Expressing Fibroblasts Facilitate Metastatic Spread of Pancreatic Cancer Through Physical Interactions

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived TGF‐β induces CLDN12 expression in cancer‐associated fibroblasts, enabling direct adhesion to pancreatic cancer cells through homophilic CLDN12 interactions, thereby promoting local invasion into adjacent tissues and metastasis to the liver; blockade with C12‐pm suppresses liver metastasis.
Qingcui Li, Xiangjing Miao, Yuanyuan Yang, Ruoyang Chen, Qingqing Fang, Xixi Duan, Xiaohan Lou, Xiaohan Yao, Lijing Zhang, Rainer Glauben, Zhihai Qin, Chen Ni   +11 more
wiley   +1 more source