Results 181 to 190 of about 106,436 (326)

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

open access: yesMedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang   +12 more
wiley   +1 more source

Pathologic and Therapeutic Schwann Cells. [PDF]

open access: yesCells
Shurin MR, Wheeler SE, Zhong H, Zhou Y.
europepmc   +1 more source

Maternal Chrono‐Nutrition and Placental DNA Methylation: The BiSC Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This is the first study to examine how the timing of a mother's meals during pregnancy relates to changes in placental DNA methylation, an epigenetic mark. We found that the timing of the last daily meal was most important. Some epigenetic changes were linked to genes involved in placental function and development, and the long‐term health consequences
Joana Llauradó‐Pont   +12 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

Interferon beta and glatiramer acetate induce proliferation of Schwann cells in vitro

open access: diamond, 2009
Renata Zanon   +2 more
openalex   +2 more sources

Metastatic malignant nerve sheath tumour in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 5‐year‐old, male, English Cream Golden Retriever dog with a 3‐month history of left thoracic limb lameness was presented to the University of Georgia Veterinary Teaching Hospital. Physical examination was unremarkable. Neurological examination indicated a left peripheral C6‒T2 lesion, but further diagnostics were declined in favour of ...
Samantha Gomez   +4 more
wiley   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang   +7 more
wiley   +2 more sources

Integrated 2D–3D Proteomic Profiling Identifies MLK4 as a Microenvironment‐Responsive Regulator of Chemotherapeutic Resistance in Human Glioblastoma Cells

open access: yesBiology of the Cell, Volume 118, Issue 5, May 2026.
Glioblastoma U251MG cells were cultured in 2D monolayers and 3D spheroids to model tumor architecture. Comparative LC–MS/MS proteomics identified proteins associated with chemoresistance in 3D conditions. Selected candidates were functionally validated by gene knockdown and drug sensitivity assays to confirm their roles in modulating glioblastoma ...
Wannawat Khotchawan   +6 more
wiley   +1 more source

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