Results 191 to 200 of about 68,795 (281)

A thermoplastic microfluidic platform with integrated electrospun scaffolds for assessing brain cell‐specific drug selectivity

VIEW, Volume 7, Issue 3, June 2026.
Schematic representation of the microfluidic platform with its advantages. Abstract A major challenge in pharmacology is the limited selectivity of therapeutic compounds toward specific tissues or cells. Drugs often distribute systemically before reaching the intended site of action, affecting nontarget cells and potentially reducing efficacy or ...
Maria Testa, Laura Palumbo, Martina La Rosa, Antonella Girgenti, Fabio Salvatore Palumbo, Pasquale Picone, Francesco Lopresti, Domenico Nuzzo, Vincenzo La Carruba   +8 more
wiley   +1 more source

Hyperglycemia Modulates mTOR Signaling and Myelin Protein Expression in Schwann Cells. [PDF]

Int J Mol Sci
Razak NHA, Vijakumaran U, Idris IM, Idris J, Hassan NH, Zaini F, Muhamad N, Daud MF.   +7 more
europepmc   +1 more source

Schwann Cell [PDF]

, 2020
openaire   +1 more source

Solitary Neurofibroma of the Hypopharynx: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Matin Ghazizadeh, Vahid Ghasem Amooeian
wiley   +1 more source

Deferoxamine Improves Radiation‐Induced Peripheral Neuropathy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Radiation‐induced peripheral neuropathy (RIPN) is a devastating sequela of radiation therapy (XRT). Current treatment options are limited. Deferoxamine (DFO) has been useful in treating radiation‐induced dermal fibrosis. This study aimed to evaluate DFO for RIPN. Thus, 18 mice received 30Gy of fractionated XRT.
Christopher V. Lavin, Alexander Z. Fazilat, Carter B. Kendig, Palca Shibale, Kelly X. Huang, Sriya Nemani, Jennifer B. Parker, Caleb Valencia, Naga A. R. Ailury, Michelle Griffin, Arash Momeni, Michael T. Longaker, Derrick C. Wan   +12 more
wiley   +1 more source

Prostaglandin E₂-driven dedifferentiation of Schwann cells leads to perineural invasion in pancreatic ductal adenocarcinoma. [PDF]

Signal Transduct Target Ther
Wang L, Liu Q, Zhang Z, Yang S, Tang J, Pan G, Zheng Y, Zhuang Y, Wu Q, Weng S, Gao F, Dong J.   +11 more
europepmc   +1 more source

Effects of imeglimin on experimental diabetic neuropathy in streptozotocin‐induced diabetic rats

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 951-960, June 2026.
Imeglimin exerted neuroprotective effects in a type 1 diabetic neuropathy model, improving sensory nerve conduction, sciatic nerve blood flow, and intraepidermal nerve fiber density. In vitro, imeglimin promoted neurite outgrowth in a DRG‐derived hybridoma cell line, supporting a direct neurotrophic action.
Wataru Nihei, Ayako Kato, Takuma Sato, Masahiro Yamaguchi, Tatsuhito Himeno, Nobuhisa Nakamura, Kazunori Sango, Keiko Naruse, Jiro Nakamura, Hideki Kamiya, Koichi Kato   +10 more
wiley   +1 more source

Effects of Methylcobalamin on Mitochondrial Alterations in Schwann Cells Under Oxidative Stress. [PDF]

Biomedicines
Li Q, Liu S, Zhang L, Sun T, Kou Y.
europepmc   +1 more source

Biallelic Nonsense Variants in NEFL May Cause a Non‐Length‐Dependent Neuropathy With Temporal Dispersion on Nerve Conduction Studies

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims Pathogenic variants in NEFL, the gene that encodes the light polypeptide subunit of neurofilaments, are an uncommon cause of autosomal recessive Charcot‐Marie‐Tooth (CMT) disease. In this study, we describe the clinical and electrophysiological features of two families with early‐onset CMT carrying nonsense variants in the ...
Marcus Vinícius Vieira da Silva Gomes, Pedro José Tomaselli, Wilson Marques Jr   +2 more
wiley   +1 more source

Sonic Hedgehog Agonists Induce Repair Schwann Cells. [PDF]

Biotechnol Bioeng
Colchado D, Schofield JB, Hunter DA, Xia X, Yang M, Sacks JM, Wood MD, Li X.   +7 more
europepmc   +1 more source