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Biology of Schwann cells

2013
The fundamental roles of Schwann cells during peripheral nerve formation and regeneration have been recognized for more than 100 years, but the cellular and molecular mechanisms that integrate Schwann cell and axonal functions continue to be elucidated.
Grahame J, Kidd   +2 more
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The Schwann Cell

1982
Although Schwann cells were not a topic in the previous series of this Handbook, their properties were covered in a general review of the peripheral nerve by Porcellati.1 In addition, aspects of protein and lipid metabolism in peripheral nerve undergoing Wallerian degeneration were reviewed.2,3 Interest in the peripheral nervous system has grown over ...
Robert M. Gould   +2 more
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Epigenetic Control of Schwann Cells

The Neuroscientist, 2018
The journey of Schwann cells from their origin in the neural crest to their ensheathment and myelination of peripheral nerves is a remarkable one. Their apparent static function in enabling saltatory conduction of mature nerve is not only vital for long-term health of peripheral nerve but also belies an innate capacity of terminally differentiated ...
Ki H. Ma, John Svaren
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Intermediate Filaments of Schwann Cells

Journal of Neurochemistry, 1982
Abstract: Intermediate filaments were prepared from distal stumps of rabbit sciatic nerve 5 weeks after nerve section, at which time Schwann cells account for 85–90% of the cell area. A polypeptide of molecular weight 58,000 was the main component of this fraction. An antiserum raised in guinea pig against this polypeptide stained all cells present in
L, Autilio-Gambetti   +3 more
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The Schwann Cell

2000
Abstract Medical eponyms often reflect a single outstanding discovery or a major contribution by the honored person to a particular field of the healing arts. The case of Theodor Schwann, however, represents a somewhat different situation.
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Schwann cells transplanted into the CNS

International Journal of Developmental Neuroscience, 1993
AbstractA small volume of purified Schwann cells, cultured from early postnatal rat sciatic nerve, was injected into the hippocampus or fimbria of syngeneic adult hosts. The procedure caused minimal structural disturbance at the transplantation site, with close graft‐host contact and maximal opportunity for integration.The donor Schwann cells were ...
G, Raisman, J M, Lawrence, G A, Brook
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Cytokine and chemokine interactions with Schwann cells: the neuroimmunology of Schwann cells

2007
INTRODUCTION Cytokines, first described as products of the cells of the inflammatory/immune system, are increasingly recognised as acting on non-inflammatory cells as well as being produced by non-inflammatory cells. Nowhere is this more apparent than with cells of the peripheral (PNS) and central (CNS) nervous systems.
Robert P. Lisak, Joyce A. Benjamins
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Developmental Regulation of Schwann Cell Precursors and Schwann Cell Generation

1997
Most myelin-forming and non-myelin-forming Schwann cells of peripheral nerves develop from the neural crest (Anderson, 1993; Bronner-Fraser, 1993; Jessen and Mirsky, 1992; Le Douarin et al., 1991; Marusich and Weston, 1991). The other main glial types in the peripheral nervous system (PNS), are also thought to be derived from the crest.
K. R. Jessen   +3 more
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Schwann Cell Dysfunction in Acromegaly

The Journal of Clinical Endocrinology & Metabolism, 1970
ABSTRACT The pathologic features observed in a sural nerve biopsy from a subject with acromegalic peripheral neuropathy are presented. Examination of individually teased nerve fibers revealed diffuse segmental demyelination. Since each internodal segment represents the territory occupied by a single Schwann cell, the presence of the segmental loss of ...
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Schwann Cell Development and Myelination

Cold Spring Harbor Perspectives in Biology
Glial cells in the peripheral nervous system (PNS), which arise from the neural crest, include axon-associated Schwann cells (SCs) in nerves, synapse-associated SCs at the neuromuscular junction, enteric glia, perikaryon-associated satellite cells in ganglia, and boundary cap cells at the border between the central nervous system (CNS) and the PNS ...
James, Salzer   +2 more
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