Gamma-oryzanol promotes neurite extension in NGF-primed PC12 cells and enhances viability/process elongation in immortalized Schwann cells. [PDF]
Shimizu T.
europepmc +1 more source
Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor‐Selective Deficits
To test the importance of lactate metabolism and shuttling between Schwann cells and neurons in the PNS, we selectively knocked out both LDHA and LDHB in motor neurons, sensory neurons, or Schwann cells. ABSTRACT Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS).
A. Joseph Bloom +11 more
wiley +1 more source
Transcriptional Profiling of Botulinum Neurotoxin Type A-Related Molecular Components in Primary Human Schwann Cells. [PDF]
Sánchez-Carranza O +3 more
europepmc +1 more source
Red Fluorescent Labeling of Myelin by Membrane‐Targeted tdTomato in Transgenic Mouse Lines
Transgenic mouse lines expressing membrane‐targeted tdTomato in myelin enable imaging of myelin in the red spectral range. Distinct expression patterns range from wide‐spread labeling to sparse single‐cell resolution, supporting diverse imaging applications.
Anja Reinert +15 more
wiley +1 more source
Retraction: Promotion of perineural invasion of cholangiocarcinoma by Schwann cells via nerve growth factor. [PDF]
Qian X +7 more
europepmc +1 more source
MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula +6 more
wiley +1 more source
Pancreatic cancer fibrosis activates protumorigenic Schwann cells through a nuclear mechanosensing mechanism. [PDF]
Stupakov P +11 more
europepmc +1 more source
ABSTRACT Background and Aims Data on cardiovascular autonomic neuropathy (CAN) are sparse in Charcot–Marie–Tooth disease. We aimed to determine the prevalence of CAN in CMT1A and CMTX1 and its associations with neuropathy severity and heart rate variability (HRV), compared with age‐ and sex‐matched controls. Methods Thirty‐six CMT1A, 24 CMTX1 patients,
Kryštof Prášil +4 more
wiley +1 more source

