Results 151 to 160 of about 106,436 (326)
Experimental Physiology, EarlyView.Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari +7 more
wiley +1 more source
CILIATED SCHWANN CELLS IN THE AUTONOMIC NERVOUS SYSTEM OF THE ADULT RAT [PDF]
, 1963 Mary A. Grillo, Sanford L. Palay
openalex +1 more source
Historical Records of Tumours in New Zealand Marine Fishes
New Zealand Journal of Marine and Freshwater Research, Volume 60, Issue 2, June 2026.Tumours were first described in New Zealand marine fishes in 1982 but those early records have been difficult to access and subsequently few tumours have been collected and little has been published. This review updates records of identified tumours from teleosts in the New Zealand marine environment and may encourage more work to identify background ...
John Brian Jones
wiley +1 more source
Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.ABSTRACT Background and Aims Pathogenic variants in NEFL, the gene that encodes the light polypeptide subunit of neurofilaments, are an uncommon cause of autosomal recessive Charcot‐Marie‐Tooth (CMT) disease. In this study, we describe the clinical and electrophysiological features of two families with early‐onset CMT carrying nonsense variants in the ...
Marcus Vinícius Vieira da Silva Gomes +2 more
wiley +1 more source
Phenol Neurolysis in Pain and Palliative Medicine
Pain Practice, Volume 26, Issue 5, June 2026.ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers +6 more
wiley +1 more source
Platelet-derived Growth Factor-BB Activates Calcium/Calmodulin-dependent and -independent Mechanisms That Mediate Akt Phosphorylation in the Neurofibromin-deficient Human Schwann Cell Line ST88-14 [PDF]
, 2013 Robert G. Farrer +2 more
openalex +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
Effect of Hyperosmotic stress on expression of aldose reductase gene in cultured rat Schwann cells
, 1998 Keiko Maekawa +5 more
openalex +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source