Transforming growth factor beta (TGF beta) mediates schwann cell death in vitro and in vivo: Examination of c-jun activation, interactions with survival signals, and the relationship of TGF beta-mediated death to schwann cell differentiation [PDF]
, 2001 In some situations, cell death in the nervous system is controlled by an interplay between survival factors and negative survival signals that actively induce apoptosis. The present work indicates that the survival of Schwann cells is regulated by such a
Bunting, H +7 more
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Monoclonal antibodies to the cells of a regenerating limb [PDF]
, 1985 Monoclonal antibodies were raised against differentiated cells, and blastemal cells from regenerating limbs of adult newts (Notophthalmus viridescens) and screened for specific staining by immunocytochemistry.
Brockes, Jeremy P., Kintner, Chris R.
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The repair Schwann cell and its function in regenerating nerves. [PDF]
, 2016 Nerve injury triggers the conversion of myelin and non-myelin (Remak) Schwann cells to a cell phenotype specialised to promote repair. Distal to damage, these repair Schwann cells provide the necessary signals and spatial cues for the survival of injured
Jessen, KR, Mirsky, R
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ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]
, 2004 Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Anderson, PN +6 more
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TGF beta type II receptor signaling controls Schwann cell death and proliferation in developing nerves [PDF]
, 2006 During development, Schwann cell numbers are precisely adjusted to match the number of axons. It is essentially unknown which growth factors or receptors carry out this important control in vivo.
D'Antonio, M +6 more
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Degeneration and regeneration of peripheral nerves: role of thrombin and its receptor PAR-1 [PDF]
, 2017 The peripheral nervous system has a striking regeneration potential and after damage extensive changes in the differentiation state both of the injured neurons and of the Schwann cells are observed.
Artico, M. +7 more
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The Ets Domain Transcription Factor Erm Distinguishes Rat Satellite Glia from Schwann Cells and Is Regulated in Satellite Cells by Neuregulin Signaling [PDF]
, 2000 Distinct glial cell types of the vertebrate peripheral nervous system (PNS) are derived from the neural crest. Here we show that the expression of the Ets domain transcription factor Erm distinguishes satellite glia from Schwann cells beginning early in ...
Baert, Jean-Luc +6 more
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Glial βii spectrin contributes to paranode formation and maintenance [PDF]
, 2018 Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D. +12 more
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The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration [PDF]
, 2015 NMDA Receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL Receptor-related Protein-1 (LRP1) to trigger cell-signaling in response to protein ligands in neurons.
Campana, W. Marie +4 more
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Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier [PDF]
, 2020 Schwann cells (SC) are characterized by a remarkable plasticity that enables them to promptly respond to nerve injury promoting axonal regeneration. In peripheral nerves after damage SC convert to a repair-promoting phenotype activating a sequence of ...
Ciraci, Viviana +9 more
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