Results 31 to 40 of about 51,731 (281)
TNFα promotes oral cancer growth, pain, and Schwann cell activation
Scientific Reports, 2021 Oral cancer is very painful and impairs a patient’s ability to eat, talk, and drink. Mediators secreted from oral cancer can excite and sensitize sensory neurons inducing pain.
Elizabeth Salvo +6 more
doaj +1 more source
Inhibition of Schwann Cell Pyroptosis Promotes Nerve Regeneration in Peripheral Nerve Injury in Rats
Mediators of Inflammation, 2023 Background. Peripheral nerve injury (PNI) is one of the most debilitating injuries, but therapies for PNI are still far from satisfactory. Pyroptosis, a recently identified form of cell death, has been demonstrated to participate in different diseases ...
Jiayi Wang +9 more
doaj +1 more source
Autophagy is involved in the reduction of myelinating Schwann cell cytoplasm during myelin maturation of the peripheral nerve. [PDF]
PLoS ONE, 2015 Peripheral nerve myelination involves dynamic changes in Schwann cell morphology and membrane structure. Recent studies have demonstrated that autophagy regulates organelle biogenesis and plasma membrane dynamics.
So Young Jang +7 more
doaj +1 more source
Lithium promotes proliferation and suppresses migration of Schwann cells
Neural Regeneration Research, 2020 Schwann cell proliferation, migration and remyelination of regenerating axons contribute to regeneration after peripheral nervous system injury. Lithium promotes remyelination by Schwann cells and improves peripheral nerve regeneration.
Xiao-Kun Gu +3 more
doaj +1 more source
Cell Transplantation, 2013 Olfactory mucosa (OM)-derived olfactory ensheathing cells (OECs) are attractive candidates for autologous cell transplantation-based therapy of nervous system injury.
Susanne Ziege +2 more
doaj +1 more source
Rab27a/Slp2-a complex is involved in Schwann cell myelination
Neural Regeneration Research, 2016 Myelination of Schwann cells in the peripheral nervous system is an intricate process involving myelin protein trafficking. Recently, the role and mechanism of the endosomal/lysosomal system in myelin formation were emphasized.
Wen-feng Su +7 more
doaj +1 more source
Notch and Schwann cell transformation [PDF]
Oncogene, 2004 Benign plexiform neurofibromas in NF1 patients can transform spontaneously into malignant peripheral nerve sheath tumors (MPNSTs). Although mutations in the p53 gene have been found in a subset of MPNSTs and mouse models support a role for p53 mutations in malignant conversion, we found that each of three Schwann cell lines derived from human MPNSTs ...
Peggy Wallace +9 more
openaire +3 more sources
Neural Regeneration Research, 2016 Schwann cells play an important role in the peripheral nervous system, especially in nerve repair following injury, so artificial nerve regeneration requires an effective technique for obtaining purified Schwann cells.
Xiao-pan Wang +5 more
doaj +1 more source
hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures
Cells, 2021 Motoneurons, skeletal muscle fibers, and Schwann cells form synapses, termed neuromuscular junctions (NMJs). These control voluntary body movement and are affected in numerous neuromuscular diseases.
Sarah Janice Hörner +5 more
doaj +1 more source
Cell Transplantation, 2001 Areas of demyelination can be remyelinated by transplanting myelin-forming cells. Schwann cells are the naturally remyelinating cells of the peripheral nervous system and have a number of features that may make them attractive for cell implantation ...
C. M. H. Brierley +6 more
doaj +1 more source