Natural and Nature-Derived Products Targeting Human Coronaviruses [PDF]
The ongoing pandemic of severe acute respiratory syndrome (SARS), caused by the SARS-CoV-2 human coronavirus (HCoV), has brought the international scientific community before a state of emergency that needs to be addressed with intensive research for the
Alexis, Michael N. +4 more
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Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications
Ginkgo biloba is an ancient plant species that is thought to provide a variety of health benefits to living organisms and contains plenty of bioactive components, making it a chemically diversified plant. G. biloba has been shown to have a variety of medicinal and pharmacological properties, including anticancer, antidementia, antidiabetic, antiobesity,
Noor-E-Tabassum +12 more
wiley +1 more source
Many indigenous Korean plants have been used in medicinal preparations and health-promoting foods. These plant species contain beneficial metabolites with various bioactivities, such as antioxidant and anti-inflammatory activities.
Se Rin Choi +8 more
doaj +1 more source
Background: In-silico analysis and molecular docking tools offer alternative ploy to characterize the virulence factors of Edwardsiella tarda and identify potential herbal antimicrobial compounds as substitutes to overcome the adverse health effects of ...
Balakrishnan Naveen Rajeshwar +1 more
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Characterisation of the biflavonoid hinokiflavone as a premRNA splicing modulator that inhibits SENP [PDF]
We have identified the plant biflavonoid hinokiflavone as an inhibitor of splicing in vitro and modulator of alternative splicing in cells. Chemical synthesis confirms hinokiflavone is the active molecule.
Abovich +51 more
core +5 more sources
Investigations on the chemical composition of volatile oils extracted from the leaves of spontaneous and cultivated Taxus baccata L. trees [PDF]
Taxus L. is accepted in the literature as natural resources of biologically active compounds and volatile oils, with applications in medicine, pharmaceuticals, food, cosmetics, and with ecological impact on the natural living environment. In this context,
BĂDULESCU, Liliana +6 more
core +2 more sources
Exploring the role of phytochemicals as biopharmaceuticals targeting Acute Respiratory Distress Syndrome (ARDS) virus: an Overview [PDF]
ALI (Acute lung injury) and its more fatal form ARDS (acute respiratory distress syndrome) together represent a broad spectrum of lung diseases, which are characterized by the abrupt onset of pulmonary inflammation with fluid filled alveoli resulting in ...
Bandyopadhyay, Subhendu +3 more
core +2 more sources
Natural products in drug discovery: meeting the urgency for new antimicrobials for human and veterinary use [PDF]
The scenario of growing microbial resistance and of lack of interest of pharmaceutical companies in developing new antimicrobial drugs jeopardizes the present and the future of the treatment of infectious diseases.
Arthur Azevedo Perpétuo +4 more
core +1 more source
Validated LC–MS/MS method for the quantification of sciadopitysin in rat plasma and its application to pharmacokinetic and bioavailability studies in vivo [PDF]
Abstract A sensitive and rapid LC–MS/MS method was developed and validated for quantitation of sciadopitysin in rat plasma using amentoflavone as an internal standard. Sample processing was accomplished after deproteinization with 150 μL aliquot of acetonitrile ...
Shenbao Yang +5 more
openaire +3 more sources
In silico molecular docking and ADMET prediction of Ginkgo biloba biflavonoids as dual inhibitors of human HMG-CoA reductase and α-amylase [PDF]
There is an increasing interest in investigating phytochemicals as inhibitors of HMG-CoA reductase (HMGR) and α-amylase enzymes. Inhibition of these enzymes helps manage hypercholesterolemia and diabetes by reducing cholesterol synthesis and blood sugar ...
Agosto Nesteve John B.
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