Results 101 to 110 of about 102,493 (259)
Abstract Aims To systematically review the evidence on the psychometric performance and accuracy of screening or diagnostic tools for cannabis use disorder. Method Systematic review and meta‐analysis which included studies conducted in clinical settings, schools, universities, community settings and population‐based surveys in multiple countries and ...
Janni Leung +8 more
wiley +1 more source
Abstract Background and aims Increased risk of alcohol dependence is recognised following bariatric surgery. Modified gastrointestinal anatomy and neurohormonal profiles lead to altered alcohol metabolism, peak blood alcohol concentrations and enhanced reward circuits and cravings.
Thomas J. Williams +4 more
wiley +1 more source
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien +15 more
wiley +1 more source
Abstract Background and Objectives Gambling in older adults represents an emerging but still underrecognized mental health concern. Although gambling participation is increasingly observed in later life, the specific psychological, social, cognitive, and biological factors associated with gambling‐related problems in older adults remain insufficiently ...
Graziella C. Prezzavento +6 more
wiley +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Abstract Objectives Internet‐delivered cognitive‐behavioural therapy (ICBT) is demonstrated to be an effective treatment for obsessive‐compulsive disorder (OCD). However, not all individuals who commence ICBT respond well to treatment and thus understanding predictors of outcome is crucial for informing best‐practice treatment planning. The aim of this
Jun Hong Lee, Bethany M. Wootton
wiley +1 more source
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam +3 more
wiley +1 more source
Background Evidence on the association between paternal smoking and attention‐deficit hyperactivity disorder (ADHD) in offspring is inconsistent. We conducted a systematic review and meta‐analysis to synthesise the available evidence. Methods This meta‐analysis was performed following the Preferred Reporting Items for Systematic Review and Meta ...
Berihun Dachew +3 more
wiley +1 more source
Review: Memory bias in adolescents with depression – a systematic review and meta‐analysis
Background Memory bias, the tendency to retrieve specific memories, is an established phenomenon in adults with depression. However, evidence on the link between depression and memory bias in children is mixed. This systematic review aimed to synthesize current knowledge examining memory bias and depression in children and adolescents.
Anett Schumacher +7 more
wiley +1 more source
ASCT2 inhibition induces ROS accumulation and activates NRF2‐dependent xCT upregulation in prostate cancer. This adaptive response partially supports residual cystine acquisition and glutathione synthesis, whereas combined ASCT2 and xCT inhibition disrupts redox compensation and predominantly promotes apoptotic cell death.
Jiaxing Wei +9 more
wiley +1 more source

