Results 111 to 120 of about 187,417 (303)
Animal Models and Experimental Medicine, EarlyView.This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin +2 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source
Humanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source
Scientific ReportsDirofilaria immitis is a mosquito-borne parasitic nematode that causes fatal heartworm disease in canids. The microfilariae are essential for research, including drug screening and mosquito-parasite interactions.
Mihoko Mizuseki +5 more
doaj +1 more source
Frontiers in ImmunologyPurposeSevere combined immunodeficiency (SCID) can be detected at birth through T-cell receptor excision circles (TREC) analysis in dried blood spots. This study summarizes the results of the consolidated SCID newborn screening (NBS) program in Catalonia
Ana Argudo-Ramírez +33 more
doaj +1 more source
Frontiers in Oncology, 2018 Within the last decade there have been several severe combined immunodeficient (SCID) pig models discovered or genetically engineered. The animals have mutations in ARTEMIS, IL2RG, or RAG1/2 genes, or combinations thereof, providing SCID pigs with NK ...
Adeline N. Boettcher +3 more
doaj +1 more source
Primary Psychoses Among Sentenced Prisoners in Finland
Criminal Behaviour and Mental Health, EarlyView.ABSTRACT Background Recent studies suggest an increased prevalence of primary psychotic disorders among sentenced prisoners in Finland. Exploring the extent and correlates of lifetime primary psychoses through high‐quality data is crucial for early identification and effective interventions within correctional settings.
Petra Laivonen +2 more
wiley +1 more source
International Medical Case Reports JournalAlamin Mustafa,1 Rogaia Hasap Alrasoul Ahmed,2 Hala Hamza Eltayeb,2 Malaz Elsadeg,2 Omaima Abdel Majeed Mohamed Salih,3 Nahla HH Erwa4 1Al-Neelain University, Faculty of Medicine, Khartoum, Sudan; 2Faculty of Medicine, Omdurman Islamic University ...
Mustafa A +5 more
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Review of Treatment for Adenosine Deaminase Deficiency (ADA) Severe Combined Immunodeficiency (SCID)
Therapeutics and Clinical Risk Management, 2022 Elizabeth Secord,1 Nicholas L Hartog2 1Pediatrics, Division of Allergy and Immunology, Wayne State University School of Medicine, Detroit, MI, USA; 2Pediatrics, Division of Allergy and Immunology, Michigan State University College of Human Medicine ...
Secord E, Hartog NL
doaj
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
, 2020 Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
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