Results 91 to 100 of about 1,477,560 (316)

Contemplation of the possibility of extending the shelf life of human immunoglobulin reference standard used for determination of anticomplementary activity

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The article gives an account of the stability study performed for two batches of human immunoglobulin reference standard (RS) used for determination of anticomplementary activity (industry reference standard, IRS 42-28-430).
O. G. Kornilova   +7 more
doaj  

Evaluation of scientific merit [PDF]

open access: yesBrazilian Oral Research, 2013
Estrela, Carlos   +1 more
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Semantically Resolving Type Mismatches in Scientific Workflows

open access: yes, 2007
Scientists are increasingly utilizing Grids to manage large data sets and execute scientific experiments on distributed resources. Scientific workflows are used as means for modeling and enacting scientific experiments.
Derouiche, Kheiredine, Nicole, Denis A
core  

New approach to the visualization of international scientific collaboration [PDF]

open access: yes, 2010
In this study, visual representations are created in order to analyze different aspects of scientific collaboration at the international level. The main objective is to identify the international facet of research by following the flow of knowledge as ...
Hassan-Montero, Yusef   +6 more
core   +1 more source

Choosing an Evaluation Theory: A Supplement to Evaluation Roots (3rd Edition)

open access: yes, 2021
Background: Unlike scientific theories, evaluation theories are prescriptive: a set of actions and approaches that should be followed when conducting an evaluation.
Christie, Christina A.   +5 more
core   +1 more source

Substantiation of conditions for determination of related substances in bisoprolol fumarate by HPLC

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article summarizes the results of information analysis of bisoprolol fumarate synthesis methods which differ in the number of stages and in raw materials used, and are associated with the major identified impurities A, E and G, according to the ...
O. A. Baturina   +7 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Scientific literacy for sustainability

open access: yes, 2006
We only need to consider public media reports to appreciate that there is growing concern amongst citizens for sustainability. This concern arises from increasing appreciation that the current direction and rate of exploitation of resources is not ...
Murcia, Karen
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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