Results 91 to 100 of about 22,645,468 (334)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Place of scientific research journals in the student research committees

open access: yesپژوهان, 2013
Place of scientific research journals in the student research ...
Hazhir Seifpanahi-sha’bani   +2 more
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Identifying reasons for failure in biomedical research and publishing

open access: yesBrazilian Journal of Medical and Biological Research, 2009
The regular assessment of Brazilian scientific output means that individual university departments need to constantly improve the quantity and quality of their scientific output. A significant proportion of this output involves the work of Master’s
D. Bousfield
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Scientific Research in Libya: The Role of the New Generation of Researchers

open access: yesLibyan Journal of Medicine, 2009
There is a potential for improving the scientific research environment in Libya. One reason to be optimistic about the prospects of the future of science in Libya is the number of postgraduate students in all disciplines who are training in European and ...
Tashani OA
doaj  

Russia-EU S&T Co-operation: a Bibliometric Analysis

open access: yesForesight and STI Governance, 2008
The expansion of international S&T cooperation is one of the prerequisites for achieving the ambitious goals of innovation development facing the Russian Federation.
Svetlana Knyazeva, Natalya Slasheva
doaj   +1 more source

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