Results 71 to 80 of about 22,645,468 (334)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Polémicas e Modelos para uma Sociologia de Intervenção

Cadernos de Estudos Africanos, 2003
The sociology of intervention has always defined its central challenge as the utopian search for the key to social change, and using this theoretical reflection, to test methods of reducing uncertainty. This has now produced a long history of theoretical,
Isabel Guerra
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

SCIENTOMETRY AND EVALUATION OF THE RESULTS OF ECONOMIC SCIENTIFIC RESEARCH [PDF]

Economica, 2017
Starting from the necessity of a continuous and demanding evaluation, capable of linking the results obtained with the human, material and financial resources, allocated and periodically setting the position of the national research relative to the ...
Ana-Lucia RISTEA, Constanta POPESCU, Valeriu IOAN-FRANC, Grigore BELOSTECINIC   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A Novel Rubric for Rating the Quality of Retraction Notices

Publications, 2014
When a scientific article is found to be either fraudulent or erroneous, one course of action available to both the authors and the publisher is to retract said article. Unfortunately, not all retraction notices properly inform the reader of the problems
Emma Bilbrey, Natalie O'Dell, Jonathan Creamer   +2 more
doaj   +1 more source

Artificial intelligence: A powerful paradigm for scientific research

The Innovation, 2021
Yongjun Xu, Qi Wang, Zhulin An, Fei Wang, Libo Zhang, Yanjun Wu, Fengliang Dong, Cheng-Wei Qiu, Xin Liu, Junjun Qiu, K. Hua, Wentao Su, Huiyu Xu, Yong Han, Xinya Cao, En-ju Liu, C. Fu, Zhigang Yin, Miao Liu, R. Roepman, S. Dietmann, M. Virta, F. Kengara, Changping Huang, Ze Zhang, Lifu Zhang, Taolan Zhao, Jianwei Dai, Jialiang Yang, L. Lan, Ming Luo, Tao Huang, Zhaofeng Liu, Sen Qian, T. An, Xingchen Liu, Bin Zhang, Xiaolei He, Shan Cong, Xiaohong Liu, Wei Zhang, Fang Wang, Chuan‐Qi Lu, Zhipeng Cai, James P. Lewis, J. Tiedje, Jia-bao Zhang   +46 more
semanticscholar   +1 more source

Human trafficking for labour exploitation: the results of a two-phase systematic review mapping the European evidence base and synthesising key scientific research evidence

Journal of Experimental Criminology, 2018
Our objectives were (1) to systematically map the contours of the European evidence base on labour trafficking, identifying its key characteristics, coverage, gaps, strengths and weaknesses and (2) to synthesise key scientific research.
E. Cockbain, K. Bowers, G. Dimitrova
semanticscholar   +1 more source

The Islamic Endowment in The Light of The Qur’an and Sunnah and its Role in The Development of Scientific Research: An Analytical Study [PDF]

, 2023
Bey Zekkoub Abdelali, Yasser Mohamed Tarshany, Fouad Bounama, Koussoube Issa   +3 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source