Inhibition of Sclerostin function by antibodies.
(A) Sclerostin-GFP was pre-incubated with Fc or the different Fabs raised against Sclerostin for 30 minutes at room temperature, next the mixtures were added to 293-LRP6 cells for 1.5h at 4°C.
Puck B. van Kasteren (408008) +10 more
core +1 more source
Sclerostin influences body composition adaptations to exercise training
Sclerostin is a secreted glycoprotein mainly produced by the osteocyte, which inhibits the canonical Wnt/ß-catenin signalling pathway. In mice, genetic deletion, or inhibition of sclerostin with a neutralizing antibody increases bone mass while also ...
Kurgan, Nigel
core
Sclerostin as a Putative Myokine in Sarcopenia
openaire +3 more sources
Intracellular sclerostin promotes tumor progression and metastasis as a potential therapeutic target in triple-negative breast cancer. [PDF]
Sun M +24 more
europepmc +1 more source
Increased Serum Levels of Dickkopf-1 and Sclerostin as WNT Signaling Pathway Inhibitors in Celiac Disease Patients. [PDF]
Al-Ani MNT +5 more
europepmc +1 more source
New findings in diabetic kidney disease: correlation and enhanced combined diagnostic value of sclerostin and 25(OH)VD. [PDF]
Niu C +7 more
europepmc +1 more source
Positive Correlates of Sclerostin and Association with Peripheral Arterial Stiffness in Patients with Type 2 Diabetes Mellitus. [PDF]
Hsu BG, Li JC, Wu DA, Chen MC.
europepmc +1 more source
Bone as an endocrine regulator of lipid and energy metabolism. [PDF]
Liu H +6 more
europepmc +1 more source

