Effects of scopolamine on matching to sample paradigm and related tests in human subjects [PDF]
, 2003 This was a double-blind placebo-controlled study with a cross-over design to examine the effects of scopolamine on cognitive functions in young healthy subjects.
Adam, M. +6 more
core +1 more source
Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum [PDF]
, 2014 Alkaloids play a key role in higher plant defense against pathogens and herbivores. Following its biosynthesis in root tissues, nicotine, the major alkaloid of Nicotiana species, is translocated via xylem transport toward the accumulation sites, leaf ...
Goossens, Alain +11 more
core +11 more sources
Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]
, 2012 As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S. +2 more
core +1 more source
Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory [PDF]
, 2016 Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Albertini, Giulia +5 more
core +2 more sources
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Oral Administration of Peppermint in Wistar Albino Rats: Memory Boosting and Regaining [PDF]
, 2013 The studies on peppermint aroma fluence on cognition are numerous. However the knowledge about oral consumption of peppermint and cognition was inadequate. Hence the present study was undertaken to find out the effect of oral administration of peppermint
Jasira, M. (M) +2 more
core +2 more sources
Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]
, 2016 Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark +5 more
core +1 more source
Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]
, 2001 This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
core +1 more source
Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes [PDF]
, 2018 The realisation of the therapeutic potential of targeting the M1 muscarinic acetylcholine receptor (M1 mAChR) for the treatment of cognitive decline in Alzheimer's disease has prompted the discovery of M1 mAChR ligands showing efficacy in alleviating ...
Bradley, Sophie J. +14 more
core +1 more source
Changes in murine anorectum signaling across the life course [PDF]
, 2018 Background: Increasing age is associated with an increase in the incidence of chronic constipation and fecal impaction. The contribution of the natural aging process to these conditions is not fully understood.
Fidalgo, S. +4 more
core +4 more sources