Results 21 to 30 of about 1,353,799 (209)

Atropine and Scopolamine in Maize Products from the Retail Stores in the Republic of Serbia

Toxins, 2022
The cereal grains, which represent the cultivated grasses fruits, supply almost half of the total caloric requirements for humans and provide more nourishment compared with any other class of the food.
Gorica Vuković, Tijana Stojanović, Bojan Konstantinović, Vojislava Bursić, Nikola Puvača, Milena Popov, Nataša Samardžić, Aleksandra Petrović, Dušan Marinković, Svetlana Roljević Nikolić, Rada Đurović Pejčev, Bojana Špirović Trifunović   +11 more
doaj   +1 more source

Thermal (In)stability of Atropine and Scopolamine in the GC-MS Inlet

Toxics, 2021
The intoxication due to unintentional or intentional ingestion of plant material containing tropane alkaloids is quite frequent. GC-MS method is still widely used for the identification of these toxicologically important substances in human specimen ...
Gordana Koželj, Helena Prosen
doaj   +1 more source

Gerberdriasins A–F, six undescribed coumarin derivatives from Gerbera anandria (Linn) Sch-Bip and their protective effects on scopolamine-induced injury in PC12 cells

RSC Advances, 2022
A chemical investigation on the herb Gerbera anandria (Linn) Sch-Bip led to the isolation and identification of six previously undescribed coumarin derivatives, named Gerberdriasins A–F (1–6).
Zhi-Li Wu, Ze-Shi Sun, Jia-yu Li, Yong-xun Yang, Xianpeng Zu, Huiliang Li, Wei-Dong Zhang   +6 more
semanticscholar   +1 more source

Investigation of Antistress and Antidepressant Activities of Synthetic Curcumin Analogues: Behavioral and Biomarker Approach

Biomedicines, 2022
Depression is a serious psychiatric disorder that affects millions of individuals all over the world, thus demanding special attention from researchers in order to investigate its effective remedies.
Haya Hussain, Shujaat Ahmad, Syed Wadood Ali Shah, Abid Ullah, Mazen Almehmadi, Osama Abdulaziz, Mamdouh Allahyani, Ahad Amer Alsaiari, Mustafa Halawi, Edrous Alamer   +9 more
doaj   +1 more source

Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease

Pharmaceuticals, 2023
Based on the multi-target-directed ligands (MTDLs) approach, two series of tryptanthrin derivatives with benzenesulfonamide substituents were evaluated as multifunctional agents for the treatment of Alzheimer’s disease (AD).
Guoxing Wang, Jiyu Du, Jie Ma, Peipei Liu, Siqi Xing, Jucheng Xia, Shuanghong Dong, Zeng Li   +7 more
doaj   +1 more source

New Myrtenal–Adamantane Conjugates Alleviate Alzheimer’s-Type Dementia in Rat Model

Molecules, 2022
Alzheimer’s disease (AD) is a neurodegenerative disease associated with memory impairment and other central nervous system (CNS) symptoms. Two myrtenal–adamantane conjugates (MACs) showed excellent CNS potential against Alzheimer’s models.
Stela Dragomanova, Maria Lazarova, Aldar Munkuev, Evgeniy Suslov, Konstantin Volcho, Nariman Salakhutdinov, Amina Bibi, Jóhannes Reynisson, Elina Tzvetanova, Albena Alexandrova, Almira Georgieva, Diamara Uzunova, Miroslava Stefanova, Reni Kalfin, Lyubka Tancheva   +14 more
doaj   +1 more source

Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
A novel class of benzamide-hydroxypyridinone (HPO) derivatives were innovatively designed, synthesised, and biologically evaluated as potential multitargeting candidates for the treatment of Alzheimer's disease (AD) through pharmacophores-merged ...
Xiaoying Jiang, Jianan Guo, Changjun Zhang, Jinping Gu, Tao Zhou, Renren Bai, Yuanyuan Xie   +6 more
doaj   +1 more source

Региоселективный синтез и свойства ацетильных производных фенолгликозидов [PDF]

, 2008
Региоселективный синтез и свойства ацетильных производных фенолгликозидов. Работа посвящена выявлению реакционной способности при кислотном дезацетилировании с использованием HCl / EtOH в CHCl3, которая приводит к дезацетилированию на O-3, O-4 и O-6 ...
Auguste, Bamber, Beadling, Behrmann, Bonifati, Brown, Cross, Damen, Derouet, Dillon, Dreuw, Fujitani, Gatsios, Gearing, Gerhartz, Gobert, Grant, Grenier, Gupta, Guschin, Haan, Heinrich, Heinrich, Hermanns, Hermanns, Hibi, Hui, Ichihara, Kuropatwinski, Lacronique, Langdon, Li, May, Miles, Mosley, Nair, Nakamura, Nakamura, Peeters, Pezet, Pflanz, Quelle, Radtke, Richards, Schwaller, Smit, Sotiropoulos, Stahl, Stevenson, Stross, Tanaka, Vernallis, Wang, Wang   +53 more
core   +2 more sources

Development of naringenin-O-alkylamine derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In this study, a series of naringenin-O-alkylamine derivatives were designed and obtained by introducing an alkylamine fragment into the naringenin skeleton.
Jing Yang, Yi Zhou, Yujuan Ban, Jing Mi, Ying He, Xinjuan Li, Zhengwei Liu, Keren Wang, Gaofeng Zhu, Wenmin Liu, Zhenghuai Tan, Zhipei Sang   +11 more
doaj   +1 more source

Production of tropane alkaloids in Hyoscyamus niger (black henbane) hairy roots grown in bubble-column and spray bioreactors [PDF]

, 2013
Hairy root cultures of Hyoscyamus niger were cultivated in shake-flasks, a bubble-column bioreactor and a hybrid bubble-column/spray bioreactor and evaluated for alkaloid production.
Adam Kokotkiewicz, Aleksandra Krolicka, Maria Luczkiewicz, Pawel Sowinski, Zbigniew Jaremicz   +4 more
core   +1 more source